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Q2FWD6

- ALD1_STAA8

UniProt

Q2FWD6 - ALD1_STAA8

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Protein
Putative aldehyde dehydrogenase SAOUHSC_02363
Gene
SAOUHSC_02363
Organism
Staphylococcus aureus (strain NCTC 8325)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei245 – 2451 By similarity
Active sitei279 – 2791 By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi201 – 2077NAD By similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciSAUR93061:GIWJ-2297-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative aldehyde dehydrogenase SAOUHSC_02363 (EC:1.2.1.3)
    Gene namesi
    Ordered Locus Names:SAOUHSC_02363
    OrganismiStaphylococcus aureus (strain NCTC 8325)
    Taxonomic identifieri93061 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000008816: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 475475Putative aldehyde dehydrogenase SAOUHSC_02363
    PRO_0000293559Add
    BLAST

    Proteomic databases

    PRIDEiQ2FWD6.

    Interactioni

    Protein-protein interaction databases

    STRINGi93061.SAOUHSC_02363.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2FWD6.
    SMRiQ2FWD6. Positions 1-475.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1012.
    HOGENOMiHOG000271505.
    KOiK00128.
    OMAiIDENRAA.
    OrthoDBiEOG6BS8QW.

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2FWD6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRDYTKQYIN GEWVESNSNE TIEVINPATE EVIGKVAKGN KADVDKAVEA    50
    ADDVYLEFRH TSVKERQALL DKIVKEYENR KDDIVQAITD ELGAPLSLSE 100
    RVHYQMGLNH FVAARDALDN YEFEERRGDD LVVKEAIGVS GLITPWNFPT 150
    NQTSLKLAAA FAAGSPVVLK PSEETPFAAV ILAEIFDKVG VPKGVFNLVN 200
    GDGAGVGNPL SEHPKVRMMS FTGSGPTGSK IMEKAAKDFK KVSLELGGKS 250
    PYIVLDDVDI KEAAKATTGK VVNNTGQVCT AGTRVLVPNK IKDAFLAELK 300
    EQFSQVRVGN PREDGTQVGP IISKKQFDQV QNYINKGIEE GAELFYGGPG 350
    KPEGLEKGYF ARPTIFINVD NQMTIAQEEI FGPVMSVITY NDLDEAIQIA 400
    NDTKYGLAGY VIGKDKETLH KVARSIEAGT VEINEAGRKP DLPFGGYKQS 450
    GLGREWGDYG IEEFLEVKSI AGYFK 475
    Length:475
    Mass (Da):51,969
    Last modified:March 21, 2006 - v1
    Checksum:i03C66ED0B87BC09A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000253 Genomic DNA. Translation: ABD31394.1.
    RefSeqiYP_500839.1. NC_007795.1.

    Genome annotation databases

    EnsemblBacteriaiABD31394; ABD31394; SAOUHSC_02363.
    GeneIDi3919406.
    KEGGisao:SAOUHSC_02363.
    PATRICi19582047. VBIStaAur99865_2140.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000253 Genomic DNA. Translation: ABD31394.1 .
    RefSeqi YP_500839.1. NC_007795.1.

    3D structure databases

    ProteinModelPortali Q2FWD6.
    SMRi Q2FWD6. Positions 1-475.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 93061.SAOUHSC_02363.

    Proteomic databases

    PRIDEi Q2FWD6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABD31394 ; ABD31394 ; SAOUHSC_02363 .
    GeneIDi 3919406.
    KEGGi sao:SAOUHSC_02363.
    PATRICi 19582047. VBIStaAur99865_2140.

    Phylogenomic databases

    eggNOGi COG1012.
    HOGENOMi HOG000271505.
    KOi K00128.
    OMAi IDENRAA.
    OrthoDBi EOG6BS8QW.

    Enzyme and pathway databases

    BioCyci SAUR93061:GIWJ-2297-MONOMER.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The Staphylococcus aureus NCTC 8325 genome."
      Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.
      (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.); Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington D.C. (2006)
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NCTC 8325.

    Entry informationi

    Entry nameiALD1_STAA8
    AccessioniPrimary (citable) accession number: Q2FWD6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 10, 2007
    Last sequence update: March 21, 2006
    Last modified: July 9, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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