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Q2FVP8 (FENR_STAA8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:SAOUHSC_02654
OrganismStaphylococcus aureus (strain NCTC 8325)
Taxonomic identifier93061 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 344344Ferredoxin--NADP reductase HAMAP MF_01685
PRO_0000364944

Sites

Binding site121FAD By similarity
Binding site311FAD By similarity
Binding site391FAD By similarity
Binding site431FAD By similarity
Binding site831FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1181FAD; via amide nitrogen By similarity
Binding site2851FAD By similarity
Binding site3261FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2FVP8 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: 46E1A319359751D3

FASTA34438,230
        10         20         30         40         50         60 
MKDVTIIGGG PSGLYASFYA GLRDMSVRLI DVQSELGGKM RIYPEKIIWD IGGIAPKPCH 

        70         80         90        100        110        120 
EILKDTIKQG LYFKPEVHLN ERVVDIRKKA ERHFEVETEA GEIYTSKAVI IAIGAGIINP 

       130        140        150        160        170        180 
KQLDVKGVER YQLTNLHYVV QSYRRFKDKD VLISGGGNTA LDWAHDIAKI AKSVTVVYRK 

       190        200        210        220        230        240 
EDVSGHEAMK TLVTDLNVKL CPKTRIKYLV GNDDETHISE VVLEHVESGD RHTVKFDDVI 

       250        260        270        280        290        300 
ISHGFDRCNT LLSETSSKLD MHDDCRVKGF GNTTTSIPGI YACGDIVYHD AKSHLIASAF 

       310        320        330        340 
SDGANAANLA KTYIQPDANA EGYVSSHHEV FKEANKTIVN KHLY

« Hide

References

[1]"The Staphylococcus aureus NCTC8325 genome."
Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCTC 8325.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000253 Genomic DNA. Translation: ABD31662.1.
RefSeqYP_501116.1. NC_007795.1.

3D structure databases

ProteinModelPortalQ2FVP8.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2FVP8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000029927; EBSTAP00000028878; EBSTAG00000029925.
GeneID3921216.
GenomeReviewsGene locus SAOUHSC_02654 in contig CP000253_GR.
KEGGsao:SAOUHSC_02654.
PATRIC19582590. VBIStaAur99865_2401.

Phylogenomic databases

eggNOGCOG0492.
GeneTreeEBGT00050000023768.
HOGENOMHBG669726.
OMAFNTSITK.
ProtClustDBCLSK885935.

Enzyme and pathway databases

BioCycSAUR93061:SAOUHSC_02654-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_STAA8
AccessionPrimary (citable) accession number: Q2FVP8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: March 21, 2006
Last modified: January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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