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Q2FU02 (Q2FU02_METHJ) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-acetyl-gamma-glutamyl-phosphate reductase HAMAP MF_00150

Short name=AGPR HAMAP MF_00150
EC=1.2.1.38 HAMAP MF_00150
Alternative name(s):
N-acetyl-glutamate semialdehyde dehydrogenase HAMAP MF_00150
Gene names
Name:argC HAMAP MF_00150
Ordered Locus Names:Mhun_3227
OrganismMethanospirillum hungatei (strain JF-1 / DSM 864)
Taxonomic identifier323259 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanospirillaceaeMethanospirillum

Protein attributes

Sequence length333 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH. HAMAP MF_00150

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. HAMAP MF_00150

Subcellular location

Cytoplasm By similarity HAMAP MF_00150.

Sequence similarities

Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. HAMAP MF_00150

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1481 By similarity HAMAP MF_00150

Sequences

Sequence LengthMass (Da)Tools
Q2FU02 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: 63E904247868F80B

FASTA33336,556
        10         20         30         40         50         60 
MRNSSMKAAI IGASGYTGGE LIRLMQSHPH VTIDVATSRQ LAGKPVTSQH PHLKGFCNLT 

        70         80         90        100        110        120 
FENPEISSLD TDIAFLAVPH TAAMAYVPDL MERGIKIIDL SADYRLPQAV FEEVYGTPHT 

       130        140        150        160        170        180 
AWKEVPYGLC ELHRDACRNA PFVSNPGCFP TGATLASAPL AKKAHTIIYD SKTGVSGAGD 

       190        200        210        220        230        240 
SPSATTHFPN VGDNLTAYKW TSHRHLAEMR QELAYLGSPA RCYFTPHLLP VNRGILTTAH 

       250        260        270        280        290        300 
ILLDEPIEQK EVEKIYQDFY RNEPFVRYQR PSLNAVRGSN FCDLMVEASE NRVVAVSVID 

       310        320        330 
NLVKGASGQA IQNMNLMCGW DETLGLMNPG MLP 

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References

[1]"Complete sequence of Methanospirillum hungatei JF-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. expand/collapse author list , Kyrpides N., Ivanova N., McInerney M.J., Brockman F., Culley D., Ferry J.G., Gunsalus R.P., Morrison M., Plugge C., Scholten J., Stams A.J.M., Boone D.R., Richardson P.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JF-1 / DSM 864.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000254 Genomic DNA. Translation: ABD42909.1.
RefSeqYP_504628.1. NC_007796.1.

3D structure databases

ProteinModelPortalQ2FU02.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2FU02.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3922120.
GenomeReviewsGene locus Mhun_3227 in contig CP000254_GR.
KEGGmhu:Mhun_3227.
NMPDRfig|323259.5.peg.3366.

Phylogenomic databases

eggNOGarNOG05044.
HOGENOMHBG294213.
OMAVCRIAVH.
PhylomeDBQ2FU02.
ProtClustDBPRK00436.

Family and domain databases

HAMAPMF_00150. ArgC_type1.
[Tree]
InterProIPR000706. AGPR_type-1.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
IPR012280. Semialdhyde_DH_dimer_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00145.
PfamPF01118. Semialdhyde_dh. 1 hit.
PF02774. Semialdhyde_dhC. 1 hit.
[Graphical view]
SMARTSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR01850. ArgC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2FU02_METHJ
AccessionPrimary (citable) accession number: Q2FU02
Entry history
Integrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: November 16, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)