ID   Q2FTU5_METHJ            Unreviewed;       829 AA.
AC   Q2FTU5;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:ABD41928.1};
GN   OrderedLocusNames=Mhun_2223 {ECO:0000313|EMBL:ABD41928.1};
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259 {ECO:0000313|EMBL:ABD41928.1, ECO:0000313|Proteomes:UP000001941};
RN   [1] {ECO:0000313|Proteomes:UP000001941}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1
RC   {ECO:0000313|Proteomes:UP000001941};
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
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DR   EMBL; CP000254; ABD41928.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2FTU5; -.
DR   STRING; 323259.Mhun_2223; -.
DR   EnsemblBacteria; ABD41928; ABD41928; Mhun_2223.
DR   KEGG; mhu:Mhun_2223; -.
DR   eggNOG; arCOG03682; Archaea.
DR   HOGENOM; CLU_367101_0_0_2; -.
DR   InParanoid; Q2FTU5; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR   PANTHER; PTHR43289:SF6; SERINE_THREONINE-PROTEIN KINASE NEKL-3; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:ABD41928.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001941};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:ABD41928.1};
KW   Transferase {ECO:0000313|EMBL:ABD41928.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        256..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          580..829
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   829 AA;  92900 MW;  5E37696B3982BFAE CRC64;
     MSSHSFFILL FFIFISFLII TPVCCVDQGS ISGITFQGGE YSSDSIPDVM YPGQNGQYMV
     EFRNTGMTAW EHDVEKIGVE YSGDSNLITV DPPLQLLPKG SRVHTGQSYQ FPFLISAHNV
     GQVKLAFAVV RLLPSGKTNR ISDPVFLSME ITTGLPHNDQ NSGSIQVTAG PLHVPVELDG
     MPAGLTPLTL PHIPVGIHHV VVKGKEGVME SDIEVKPNSI HSITYSPEKS GVLIETKESL
     LLENSNPVLT LILSNFFIIL GVIITLTTVA VISIVVISGE IKRIKFVVSH VLPSSVQKES
     GRDFAIETRR RISSDDVRFD PVAGLFKQGD KKSLKLKITN MGTKPIVVDT IRIEPGVCRI
     VFREIFDDDP GDCEVSQAVS YIDGNGKEKS RVIHLQYRIM PRDLDLSWFF ERFIQKKGNI
     IAILKIKNNN PFPLEADSIL LASGEERGIE LVMDVPDSDE LSVYKKLRIL TENEYSFPLS
     VKIPYNKGIF LFFSKKYSES LEWFNQQIDL GNDDGTLKRY RDLIKRKMDS SSEVNTMDSS
     DIRDHEPDVK RKVDAQEGNA TQVSLSPSLT GFPDSLLPIY KPSALISTDR LGIMYRALRA
     ADNIEVAVRV LDSGVIPASQ VELQIQAWRS LKHMNIMQIK FWERDPVYFL EFDLPSGAIQ
     SKKRIYSLAD LKVPIPARAA LRIVRGLAEG IDYIHRQGVR HYLLEPSVIF LDDGLQPKIS
     GFDTSALIQS GIPDDCWVIA PEQRNPEKFG NPGKKTDIYQ VGAIFYYLLS GQVLNCFESI
     SSLPSHFRSD YGVYDPIIKK SVHIDKNERY GDIREMIHEI DTLLQTFKK
//