ID   Q2FTU3_METHJ            Unreviewed;       681 AA.
AC   Q2FTU3;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:ABD41930.1};
GN   OrderedLocusNames=Mhun_2225 {ECO:0000313|EMBL:ABD41930.1};
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259 {ECO:0000313|EMBL:ABD41930.1, ECO:0000313|Proteomes:UP000001941};
RN   [1] {ECO:0000313|Proteomes:UP000001941}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1
RC   {ECO:0000313|Proteomes:UP000001941};
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
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DR   EMBL; CP000254; ABD41930.1; -; Genomic_DNA.
DR   RefSeq; WP_011449188.1; NC_007796.1.
DR   AlphaFoldDB; Q2FTU3; -.
DR   STRING; 323259.Mhun_2225; -.
DR   EnsemblBacteria; ABD41930; ABD41930; Mhun_2225.
DR   GeneID; 25393556; -.
DR   KEGG; mhu:Mhun_2225; -.
DR   eggNOG; arCOG03682; Archaea.
DR   HOGENOM; CLU_367101_0_0_2; -.
DR   InParanoid; Q2FTU3; -.
DR   OrthoDB; 41005at2157; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR045269; Atg1-like.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR013229; PEGA.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   PANTHER; PTHR24348:SF22; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR   PANTHER; PTHR24348; SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED; 1.
DR   Pfam; PF08308; PEGA; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:ABD41930.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001941};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:ABD41930.1};
KW   Transferase {ECO:0000313|EMBL:ABD41930.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        258..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          412..678
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          315..395
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        337..381
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   681 AA;  75772 MW;  E435FAF8F759216A CRC64;
     MSGTNQNWMN MSMAGPIFLT LLVFMVPGVY AADDLFGMGG TSGVGYYKGD YVSDTIPSSL
     EAGSSYPVVI SFQNNGMVSW EWGVEKFGLL YQGLQSSITV DPVFSPIPAG MKVATQEEIS
     FPFVLTPPDK PGEYELSFSM STRKGEDKYT PFPNGFTKKI IVIPKEGVSS GNVGSIIIQS
     NPTGAMVSMG SEEKGKTPLT LPDLNPAQYE ITVSHPDYGR KWAQVRVEPG SVSRVTVDLT
     TSEKPVVSTE QLLKFTPLGW LLDNISLIII SIIILFFGFQ VIMMDTKRIP EHHPVRRYTR
     PLILLAPYAD GKSRFQRGLS KDGRGESTGG GADASGGADG DRRREQGKTA GSESGTRKSV
     RDRKIRRDGE SSERKPIETE EDESLPDVED PDQEGREIEG IYGFPHALRD RYEPLGVAGD
     DTYARVYKVR KKESGDVRAL KVGHSKQPGS EILQKESAVW RSLRHPNIVH LFKSEFLDDM
     SYLENEYLDG VSYKGMVHTS LNGLPKPIRE QYAVSLVRDI AEGLKYAHDV GVRHYHLQSG
     DILLTPKLRA KVSGFARGRN ELGFSVKDSD VRGATAAFIT PEQRDEQKYG NPGRRTDIYQ
     LGVIFYELLT GYLPYSPEAF QKSGHEGTFE DHADELILPS AFRKSLEKYD PIIVRMLSRK
     KSGRYYLMDE FIKDLDSVRK A
//