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Q2FTS9 (Q2FTS9_METHJ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
5,10-methylenetetrahydromethanopterin reductase HAMAP MF_01091
EC=1.5.99.11 HAMAP MF_01091
Alternative name(s):
Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase HAMAP MF_01091
Methylene-H(4)MPT reductase HAMAP MF_01091
Gene names
Name:mer HAMAP MF_01091
Ordered Locus Names:Mhun_2257
OrganismMethanospirillum hungatei (strain JF-1 / DSM 864)
Taxonomic identifier323259 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanospirillaceae › Methanospirillum

Protein attributes

Sequence length328 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible reduction of methylene-H4MPT to methyl-H4MPT By similarity. HAMAP MF_01091

Catalytic activity

5-methyltetrahydromethanopterin + coenzyme F420 = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420. HAMAP MF_01091

Pathway

One-carbon metabolism; methanogenesis from CO(2); methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 1/2. HAMAP MF_01091

Subcellular location

Cytoplasm By similarity HAMAP MF_01091.

Sequence similarities

Belongs to the mer family. HAMAP MF_01091

Sequences

Sequence LengthMass (Da)Tools
Q2FTS9 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: 8E0ED4B188C1FB56

FASTA32834,884
        10         20         30         40         50         60 
MSYGIEFVPG NITVKQVVNY CKLAESKDID FAWITNHYNN RHCYPTLAAI AQETTTLKMG 

        70         80         90        100        110        120 
PGIMNAFTDT PAAMASFACT LNEISDGRAV MGIGPGDLST LPKLAINPEK PVGRLEEAVV 

       130        140        150        160        170        180 
QMRKLWGGEE VKKSGMKFFD YDGAKLTGVS LPGKKGIPVY IGAQGPKVLE LAGTIGDGAL 

       190        200        210        220        230        240 
INASNPKDFD VAIPIIKAAC EKVGKKGFDI GAYTAMSIDM NEKKARNAAK IVAAFIAAGS 

       250        260        270        280        290        300 
PEPLLQRHGL DLAKVANIKA ALAKFDFKTA GENVDDATID AFTIAGNPDT VKQKCEDLLK 

       310        320 
SGVTQIIFGS PLGPDMVNSI RLLGKYVV

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References

[1]"Complete sequence of Methanospirillum hungatei JF-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. expand/collapse author list , Kyrpides N., Ivanova N., McInerney M.J., Brockman F., Culley D., Ferry J.G., Gunsalus R.P., Morrison M., Plugge C., Scholten J., Stams A.J.M., Boone D.R., Richardson P.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JF-1 / DSM 864.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000254 Genomic DNA. Translation: ABD41962.1.
RefSeqYP_503681.1. NC_007796.1.

3D structure databases

ProteinModelPortalQ2FTS9.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2FTS9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3924218.
GenomeReviewsGene locus Mhun_2257 in contig CP000254_GR.
KEGGmhu:Mhun_2257.
NMPDRfig|323259.5.peg.2381.

Phylogenomic databases

eggNOGarNOG04928.
HOGENOMHBG497169.
OMAGIEFVPG.
ProtClustDBPRK02271.

Family and domain databases

HAMAPMF_01091. F420_mer.
[Tree]
InterProIPR011251. Luciferase-like_dom.
IPR019946. MeH4methanopterin_reductase.
[Graphical view]
Gene3DG3DSA:3.20.20.30. Luciferase_like. 1 hit.
KOK00320.
PfamPF00296. Bac_luciferase. 1 hit.
[Graphical view]
SUPFAMSSF51679. Luciferase_like. 1 hit.
TIGRFAMsTIGR03555. F420_mer. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2FTS9_METHJ
AccessionPrimary (citable) accession number: Q2FTS9
Entry history
Integrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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