Q2FT49 (Q2FT49_METHJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Ordered Locus Names:

Mhun_3055

Organism

Methanospirillum hungatei (strain JF-1 / DSM 864)

Taxonomic identifier

323259 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanospirillaceae › Methanospirillum

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Molecular function	Ligase RuleBase RU004370 EMBL ABD42742.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2FT49 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: 9734F1AE5D4958CF	FASTA	330	35,523
	10 20 30 40 50 60 MEQDAYREAG VDIDLEAAAV KSLISELTYR RTDQFGMASE IGHFAGFISF GKYVLAMAVD 70 80 90 100 110 120 GVGTKMLVAD ALQDWSTVGI DCIAMNVNDL YVMNLEPVAF VDYIATSELS QEQMRQIGKG 130 140 150 160 170 180 LNEGARQANL SILGGETATL KGLVTGLDLA GACLGIQEKE KVISGSAITP GDCMVGIPSS 190 200 210 220 230 240 GIHSNGLTLA RRMVEQHGSY SDRLPSGATL GDELLRPTRI YADAIQVCAE TAVHGMCHIT 250 260 270 280 290 300 GGGLLNLNRL GEFGYVFDAP LPPQEIFEWI AKAGQISEPE MYRTFNMGMG YVFILPKEGV 310 320 330 KTVQKYFPDA QIVGHITGTP GIRLNGKKLF

References

[1]

"Complete sequence of Methanospirillum hungatei JF-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. , Kyrpides N., Ivanova N., McInerney M.J., Brockman F., Culley D., Ferry J.G., Gunsalus R.P., Morrison M., Plugge C., Scholten J., Stams A.J.M., Boone D.R., Richardson P. Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JF-1 / DSM 864.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000254 Genomic DNA. Translation: ABD42742.1.
RefSeq	YP_504461.1. NC_007796.1.
3D structure databases
ProteinModelPortal	Q2FT49.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2FT49.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3923463.
GenomeReviews	Gene locus Mhun_3055 in contig CP000254_GR.
KEGG	mhu:Mhun_3055.
NMPDR	fig|323259.5.peg.3197.
Phylogenomic databases
eggNOG	arNOG04189.
HOGENOM	HBG531222.
OMA	GIDMIAM.
PhylomeDB	Q2FT49.
ProtClustDB	CLSK949966.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2FT49_METHJ

Accession

Primary (citable) accession number: Q2FT49

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)