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Q2FT11 (Q2FT11_METHJ) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Methenyltetrahydromethanopterin cyclohydrolase HAMAP-Rule MF_00486
EC=3.5.4.27 HAMAP-Rule MF_00486
Alternative name(s):
Methenyl-H4MPT cyclohydrolase HAMAP-Rule MF_00486
Gene names
Name:mch HAMAP-Rule MF_00486
Ordered Locus Names:Mhun_2384 EMBL ABD42086.1
OrganismMethanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1) [Reference proteome] [HAMAP] EMBL ABD42086.1
Taxonomic identifier323259 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanospirillaceae › Methanospirillum ›

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible interconversion of 5-formyl-H4MPT to methenyl-H4MPT+ By similarity. HAMAP-Rule MF_00486

Catalytic activity

5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = 5-formyl-5,6,7,8-tetrahydromethanopterin. HAMAP-Rule MF_00486

Pathway

One-carbon metabolism; methanogenesis from CO(2); 5,10-methenyl-5,6,7,8-tetrahydromethanopterin from CO(2): step 3/3. HAMAP-Rule MF_00486

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00486.

Sequence similarities

Belongs to the MCH family. HAMAP-Rule MF_00486

Sequences

Sequence LengthMass (Da)Tools
Q2FT11 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: F7C58BDD9F624C6F

FASTA31834,850
        10         20         30         40         50         60 
MISVNTNALP VVLDMIRNAE ILGIKVHSLE NGATLIDCGV MENGCHEAGL QFLKVCAGGL 

        70         80         90        100        110        120 
IEPTIVHQPI AGQIFPFVHL TVKHPIIACL GSQKAGWVIK RNRFFAMGSG PARALALKPK 

       130        140        150        160        170        180 
GTYQAIQYYD TSDVAIITLE AGMLPDAEVC EYIADKCGVK PSCLYALVAS TRSIVGSIQI 

       190        200        210        220        230        240 
SGRIVTMAMH KLEDMGYDLS NIVNAAGRSP VAPVKRTFEQ AMGVTNDCNI YYGSVIISTR 

       250        260        270        280        290        300 
FYSDDFSRIT SDNSEMYGRP FYELFRNANY DIVNIGSYLG FSPAELTVND CTTGKIYHFG 

       310 
RLNEEVLLES FQATYERV

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References

[1]"Complete sequence of Methanospirillum hungatei JF-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. expand/collapse author list , Kyrpides N., Ivanova N., McInerney M.J., Brockman F., Culley D., Ferry J.G., Gunsalus R.P., Morrison M., Plugge C., Scholten J., Stams A.J.M., Boone D.R., Richardson P.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27890 / DSM 864 / NBRC 100397 / JF-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000254 Genomic DNA. Translation: ABD42086.1.
RefSeqYP_503805.1. NC_007796.1.

3D structure databases

ProteinModelPortalQ2FT11.
ModBaseSearch...

Protein-protein interaction databases

STRING323259.Mhun_2384.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD42086; ABD42086; Mhun_2384.
GeneID3923282.
KEGGmhu:Mhun_2384.

Phylogenomic databases

eggNOGCOG3252.
HOGENOMHOG000224079.
KOK01499.
ProtClustDBPRK02264.

Enzyme and pathway databases

BioCycMHUN323259:GH0L-2416-MONOMER.
UniPathwayUPA00640; UER00694.

Family and domain databases

HAMAPMF_00486. McH.
InterProIPR003209. METHMP_CycHdrlase.
[Graphical view]
PfamPF02289. MCH. 1 hit.
[Graphical view]
SUPFAMSSF56199. Cyclohydrolase. 1 hit.
TIGRFAMsTIGR03120. one_C_mch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2FT11_METHJ
AccessionPrimary (citable) accession number: Q2FT11
Entry history
Integrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: May 29, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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