SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2FSY4

- Q2FSY4_METHJ

UniProt

Q2FSY4 - Q2FSY4_METHJ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ribulose bisphosphate carboxylase

Gene
rbcL, Mhun_2315
Organism
Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the addition of molecular CO2 and H2O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase By similarity.UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381Proton acceptor By similarityUniRule annotation
Binding sitei140 – 1401Substrate By similarityUniRule annotation
Metal bindingi164 – 1641Magnesium; via carbamate group By similarityUniRule annotation
Metal bindingi166 – 1661Magnesium By similarityUniRule annotation
Metal bindingi167 – 1671Magnesium By similarityUniRule annotation
Active sitei255 – 2551Proton acceptor By similarityUniRule annotation
Binding sitei256 – 2561Substrate By similarityUniRule annotation
Binding sitei288 – 2881Substrate By similarityUniRule annotation
Sitei295 – 2951Transition state stabilizer By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. ribulose-bisphosphate carboxylase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbon fixation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported, OxidoreductaseUniRule annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciMHUN323259:GH0L-2343-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylaseUniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCOUniRule annotation
Gene namesi
Name:rbcLUniRule annotation
Ordered Locus Names:Mhun_2315Imported
OrganismiMethanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)Imported
Taxonomic identifieri323259 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanospirillaceaeMethanospirillum
ProteomesiUP000001941: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei164 – 1641N6-carboxylysine By similarityUniRule annotation

Interactioni

Subunit structurei

Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi323259.Mhun_2315.

Structurei

3D structure databases

ProteinModelPortaliQ2FSY4.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni325 – 3273Substrate binding By similarityUniRule annotation
Regioni347 – 3504Substrate binding By similarityUniRule annotation

Sequence similaritiesi

Belongs to the RuBisCO large chain family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1850.
HOGENOMiHOG000230832.
KOiK01601.
OMAiFTQDWAS.

Family and domain databases

Gene3Di3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
InterProiIPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamiPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMiSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2FSY4-1 [UniParc]FASTAAdd to Basket

« Hide

MTDVIATYYF RPREGVTPEW AAQAIAEEQT TGTWTDISTR QNYVHYLDGV    50
VDEIHPSGGG YTCTIRYPSE IFEPGNIPQY LSVLAGNLFG LSRIAAVRLV 100
DVEFSRDIVP FKGPKFGIEG VRKLAGTVDR PHVGTIIKPK VGLNPKDTAA 150
VAYEAAIGGV DLIKDDETLT DQAFCPLGER LPLIMEQLDR VKSETGRNVL 200
YAVNISSAGD KIVQRAREAA RMGANMLMID VIVCGFDAVR AVAEEPGINL 250
PIHVHRTMHA AITRNPEHGI AMRPICRLVR MLGGDQLHTG TVSGKMEHDV 300
TELRGDNLAL TEPFFDLKPT FPVASGGLHP GGVHKEVSML GRDIILQAGG 350
GIHGHPDGTR VGATAMRQAV DAAVAGISPA TYAEDHPELK RALDKWGIA 399
Length:399
Mass (Da):43,121
Last modified:March 21, 2006 - v1
Checksum:i23E9553185B5A593
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000254 Genomic DNA. Translation: ABD42020.1.
RefSeqiYP_503739.1. NC_007796.1.

Genome annotation databases

EnsemblBacteriaiABD42020; ABD42020; Mhun_2315.
GeneIDi3922057.
KEGGimhu:Mhun_2315.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000254 Genomic DNA. Translation: ABD42020.1 .
RefSeqi YP_503739.1. NC_007796.1.

3D structure databases

ProteinModelPortali Q2FSY4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 323259.Mhun_2315.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD42020 ; ABD42020 ; Mhun_2315 .
GeneIDi 3922057.
KEGGi mhu:Mhun_2315.

Phylogenomic databases

eggNOGi COG1850.
HOGENOMi HOG000230832.
KOi K01601.
OMAi FTQDWAS.

Enzyme and pathway databases

BioCyci MHUN323259:GH0L-2343-MONOMER.

Family and domain databases

Gene3Di 3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
InterProi IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view ]
Pfami PF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27890 / DSM 864 / NBRC 100397 / JF-1.

Entry informationi

Entry nameiQ2FSY4_METHJ
AccessioniPrimary (citable) accession number: Q2FSY4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: September 3, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O2 to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains By similarity.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi