Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cysteate synthase

Gene

Mhun_2977

Organism
Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.UniRule annotation

Catalytic activityi

O-phospho-L-serine + sulfite = L-cysteate + phosphate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

Pathwayi: coenzyme M biosynthesis

This protein is involved in the pathway coenzyme M biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway coenzyme M biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei131Pyridoxal phosphateUniRule annotation1
Binding sitei379Pyridoxal phosphateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processCoenzyme M biosynthesis
LigandPyridoxal phosphate

Enzyme and pathway databases

BioCyciMHUN323259:G1G5Z-3155-MONOMER
UniPathwayiUPA00355

Names & Taxonomyi

Protein namesi
Recommended name:
Cysteate synthaseUniRule annotation (EC:2.5.1.76UniRule annotation)
Short name:
CSUniRule annotation
Short name:
Cya synthaseUniRule annotation
Gene namesi
Ordered Locus Names:Mhun_2977
OrganismiMethanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Taxonomic identifieri323259 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanospirillaceaeMethanospirillum
Proteomesi
  • UP000001941 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003926551 – 422Cysteate synthaseAdd BLAST422

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei105N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Subunit structurei

Homotrimer.UniRule annotation

Protein-protein interaction databases

STRINGi323259.Mhun_2977

Structurei

3D structure databases

ProteinModelPortaliQ2FSC3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the threonine synthase family. Cysteate synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01434 Archaea
COG0498 LUCA
HOGENOMiHOG000226437
KOiK15527
OMAiDGMGTVM
OrthoDBiPOG093Z08UZ

Family and domain databases

HAMAPiMF_02109 Cya_synthase, 1 hit
InterProiView protein in InterPro
IPR022401 Cysteate_synthase
IPR001926 PLP-dep
IPR036052 Trypto_synt_PLP_dependent
PfamiView protein in Pfam
PF00291 PALP, 1 hit
SUPFAMiSSF53686 SSF53686, 1 hit
TIGRFAMsiTIGR03844 cysteate_syn, 1 hit

Sequencei

Sequence statusi: Complete.

Q2FSC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGYTLTCPV CNKEFSDSYT LTCPGGCQGL IRAKYAARQI TLHDAPGVFK
60 70 80 90 100
YMDWLPVTGV LRTRAEPVCF KSEGLARALG LSDLWIVFSG YWPEVGAFAV
110 120 130 140 150
SGSFKEFEAF PTMQRLSERT KGIIQVSSAG NTGRAFAEVS AETCQPVIIV
160 170 180 190 200
VPESARDRLF TTSPAHDTLL ITISGDYTDA INLGSRICTL PGIFPEGGAK
210 220 230 240 250
NVARRDGMGT VMLAGTLAMG TLPDWYLQAV GSGTGGIAAY EASLRLIADG
260 270 280 290 300
RFGTRMPRLL LFQNEPFIPM VRAWQEKRRE IKDEDMPDAE QAISQVYSDV
310 320 330 340 350
LTNRTPPYGI VGGVFDTLIA TNGLMAGVSS ADAQEAGKLF SSSEGIDPDP
360 370 380 390 400
AAAVCVAGLM RAVRSGVIKP DEKILLNITG GGYARGRKDL PRFVKAPDIM
410 420
VSKETPFEKI SAKVQEWMRY YA
Length:422
Mass (Da):45,660
Last modified:March 21, 2006 - v1
Checksum:iAFB64CF5F7C5B2C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000254 Genomic DNA Translation: ABD42664.1
RefSeqiWP_011449917.1, NC_007796.1

Genome annotation databases

EnsemblBacteriaiABD42664; ABD42664; Mhun_2977
GeneIDi3922460
KEGGimhu:Mhun_2977

Entry informationi

Entry nameiCYAS_METHJ
AccessioniPrimary (citable) accession number: Q2FSC3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: March 21, 2006
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health