Reviewed, UniProtKB/Swiss-Prot Q2FS97 (IF6_METHJ)

Names and origin

Protein names

Recommended name:
Translation initiation factor 6
Short name=aIF-6

Gene names

Name:	eif6
Ordered Locus Names:	Mhun_3020

Organism

Methanospirillum hungatei (strain JF-1 / DSM 864) [Complete proteome] [HAMAP]

Taxonomic identifier

323259 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanospirillaceae › Methanospirillum

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex By similarity. HAMAP MF_00032
Sequence similarities	Belongs to the eIF-6 family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mature ribosome assembly Inferred from electronic annotation. Source: InterPro translational initiation Inferred from electronic annotation. Source: HAMAP
Molecular function	ribosome binding Inferred from electronic annotation. Source: InterPro translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 221	221	Translation initiation factor 6 HAMAP MF_00032		PRO_0000259431

Sequences

	Sequence		Length	Mass (Da)
	Q2FS97-1 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: 24D7E3CADEC1F112	FASTA	221	23,654
	10 20 30 40 50 60 MDRFVSIAGD PHIGVFTRVF DDIAVVPPDV PEEVTTRYEE ALKVEIVRTT IQRSPIIGSL 70 80 90 100 110 120 LVGNNNGLVI TGMATEEEIA TLSEYRDLML LEEGMNAAGN IILANDHFAA VHPEMDEEFM 130 140 150 160 170 180 DALSDFLKVP VIPLTLGDVK TVGMAAVATN SGVVVSPRTT PGEIQRLEQV CSLPVGKGTV 190 200 210 220 TMGNAMVGTG LVANRYGYLA GVGTSGYELG RIEDILGFEE E

References

[1]

"Complete sequence of Methanospirillum hungatei JF-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. , Kyrpides N., Ivanova N., McInerney M.J., Brockman F., Culley D., Ferry J.G., Gunsalus R.P., Morrison M., Plugge C., Scholten J., Stams A.J.M., Boone D.R., Richardson P. Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000254 Genomic DNA. Translation: ABD42707.1.
RefSeq	YP_504426.1.
3D structure databases
SMR	Q2FS97. Positions 1-217.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2FS97.
Genome annotation databases
GeneID	3922842.
GenomeReviews	Gene locus Mhun_3020 in contig CP000254_GR.
KEGG	mhu:Mhun_3020.
NMPDR	fig|323259.5.peg.3158.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG10240.
HOGENOM	HBG589638.
OMA	QFENSNE.
PhylomeDB	Q2FS97.
ProtClustDB	PRK04046.
Family and domain databases
HAMAP	MF_00032. eIF-6. [Tree]
InterPro	IPR002769. eIF6. [Graphical view]
PANTHER	PTHR10784. eIF6. 1 hit.
Pfam	PF01912. eIF-6. 1 hit. [Graphical view]
PIRSF	PIRSF006413. IF-6. 1 hit.
SMART	SM00654. eIF6. 1 hit. [Graphical view]
TIGRFAMs	TIGR00323. eIF-6. 1 hit.
ProtoNet	Search...

Entry information

Entry name

IF6_METHJ

Accession

Primary (citable) accession number: Q2FS97

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	March 21, 2006
Last modified:	March 2, 2010
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)