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Q2FS66

- SYR_METHJ

UniProt

Q2FS66 - SYR_METHJ

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMHUN323259:GH0L-2878-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Mhun_2837
OrganismiMethanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Taxonomic identifieri323259 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanospirillaceaeMethanospirillum
ProteomesiUP000001941: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 555555Arginine--tRNA ligasePRO_0000242132Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi323259.Mhun_2837.

Structurei

3D structure databases

ProteinModelPortaliQ2FS66.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi117 – 12711"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247213.
KOiK01887.
OMAiMEHMGFG.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2FS66-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYRTTCDAIA AILRQHTGKE DVMLTDGGDH ADVASTIAFS LAKELRKAPA
60 70 80 90 100
IIAQEIAGAI SDQVMAETGA ETRAVGPYVN FIFGAEYCMN VLEQAVREGY
110 120 130 140 150
GKGQEKSERV VLEHTSANPN GPLHVGHIRN TIIGDTLARC FRKAGYPLEV
160 170 180 190 200
QYYVNDMGRQ IAIVAWGIAT QGADIHAEGK GDHLIADVYI EANRHLEKEP
210 220 230 240 250
ALNAEIDRLM QLVESGDPDT ISQFKIPVKR CLDGFKDTLA AMHVKHDRFI
260 270 280 290 300
YESDFIRNGD TAKVLSRISH LPEARIEETL SLDLSAFGFE KNYILRRSDG
310 320 330 340 350
TSVYAARDIA FHIWKGHNFD RVIDVLGADH KLIGTQLQAT LEILGERVPE
360 370 380 390 400
IVFFEFVSLP EGSMSTRKGK FISADELIAE TERRAMEEVT ARRSELSEEE
410 420 430 440 450
RKKIAHSVAI SAIRYDIIRT IPEKSTVFDW KEALDFEKQS GPYIQYAHAR
460 470 480 490 500
ACSILEKAES YTPCFEAEGE GEIALTKQIA LFPKVITEVV TELKPHLLAI
510 520 530 540 550
YARELADIFN SFYHAEPVLR AEGKIRDRRL TLVDATRNTL KEALETLGID

ALRAM
Length:555
Mass (Da):61,994
Last modified:March 21, 2006 - v1
Checksum:i22FFA23E06B51378
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000254 Genomic DNA. Translation: ABD42529.1.
RefSeqiWP_011449783.1. NC_007796.1.
YP_504248.1. NC_007796.1.

Genome annotation databases

EnsemblBacteriaiABD42529; ABD42529; Mhun_2837.
GeneIDi3923106.
KEGGimhu:Mhun_2837.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000254 Genomic DNA. Translation: ABD42529.1 .
RefSeqi WP_011449783.1. NC_007796.1.
YP_504248.1. NC_007796.1.

3D structure databases

ProteinModelPortali Q2FS66.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 323259.Mhun_2837.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD42529 ; ABD42529 ; Mhun_2837 .
GeneIDi 3923106.
KEGGi mhu:Mhun_2837.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247213.
KOi K01887.
OMAi MEHMGFG.

Enzyme and pathway databases

BioCyci MHUN323259:GH0L-2878-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27890 / DSM 864 / NBRC 100397 / JF-1.

Entry informationi

Entry nameiSYR_METHJ
AccessioniPrimary (citable) accession number: Q2FS66
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 21, 2006
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3