ID   Q2FRY2_METHJ            Unreviewed;       417 AA.
AC   Q2FRY2;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:ABD42364.1};
GN   OrderedLocusNames=Mhun_2667 {ECO:0000313|EMBL:ABD42364.1};
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259 {ECO:0000313|EMBL:ABD42364.1, ECO:0000313|Proteomes:UP000001941};
RN   [1] {ECO:0000313|Proteomes:UP000001941}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1
RC   {ECO:0000313|Proteomes:UP000001941};
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
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DR   EMBL; CP000254; ABD42364.1; -; Genomic_DNA.
DR   RefSeq; WP_011449620.1; NC_007796.1.
DR   AlphaFoldDB; Q2FRY2; -.
DR   STRING; 323259.Mhun_2667; -.
DR   EnsemblBacteria; ABD42364; ABD42364; Mhun_2667.
DR   GeneID; 25393570; -.
DR   KEGG; mhu:Mhun_2667; -.
DR   eggNOG; arCOG03682; Archaea.
DR   HOGENOM; CLU_658267_0_0_2; -.
DR   InParanoid; Q2FRY2; -.
DR   OrthoDB; 41005at2157; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR   PANTHER; PTHR43289:SF6; SERINE_THREONINE-PROTEIN KINASE NEKL-3; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:ABD42364.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001941};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:ABD42364.1};
KW   Transferase {ECO:0000313|EMBL:ABD42364.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        62..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        91..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        124..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          174..417
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   417 AA;  46129 MW;  D3DF151CF4DE39C4 CRC64;
     MKTTIFPGPD LSLRKKSLYM WGVLIIHLLL AFQYLLVEFL FLSAPIRHGH GGGQGLGNAI
     NLSLPSFSIL FMLLILCHII SLVGARHSIR FIIGSGFGLV ITATLTLGLL LFSRQSMNLL
     EMVYSHAILV IISLICSLLI GIYMVISQVW KGHGNENIRQ GRDISSFPLP MNRYRNVRPI
     GEGGVGRIWY AERTGDGTPV VVKVPRTDDE MTGLSFMQEI SIWRDLEHPH IATLLSANIL
     PVPYIEIEYL PRSVADLKTP HPIPQALQII QGLVSALIYA HGRGVIHCDI KPTNILLTHE
     GMVKLTDWGL ARSGRDRRSV SGFSPTYAAP EQRSVYSECT APTDIWQVGM VCAELLTGRP
     EIPSGTEPVF QTGEGEKLLS IILKCLVSDP AGRYQSIREL SVDLERIAPE RSDDSGY
//