Q2FQM7 (DCD_METHJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Mhun_1008

Organism

Methanospirillum hungatei (strain JF-1 / DSM 864)

Taxonomic identifier

323259 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanospirillaceae › Methanospirillum

Protein attributes

Sequence length	185 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 185	185	Probable deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000117982

Sequences

	Sequence		Length	Mass (Da)
	Q2FQM7 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: 259EAB2F283158D2	FASTA	185	20,901
	10 20 30 40 50 60 MILVDWQITD RIERGYIGID PYNPELIQPN SIDIRLGNHF VWYTPGDEII DPYIRDTVTG 70 80 90 100 110 120 GTEEMTAESI VLHPGQFVLA ETMEAIRLPD NIVASIEGKS SIARLGIELH QTGGWIDAGF 130 140 150 160 170 180 AGSITLEMCN VNQRPVRMHA GMPIGQLVFY TTERALCPYN AKKDAKYLNQ RQATLSRYYE NKKRA

References

[1]

"Complete sequence of Methanospirillum hungatei JF-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. , Kyrpides N., Ivanova N., McInerney M.J., Brockman F., Culley D., Ferry J.G., Gunsalus R.P., Morrison M., Plugge C., Scholten J., Stams A.J.M., Boone D.R., Richardson P. Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JF-1 / DSM 864.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000254 Genomic DNA. Translation: ABD40758.1.
RefSeq	YP_502477.1. NC_007796.1.
3D structure databases
ProteinModelPortal	Q2FQM7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2FQM7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3924568.
GenomeReviews	Gene locus Mhun_1008 in contig CP000254_GR.
KEGG	mhu:Mhun_1008.
NMPDR	fig|323259.5.peg.1062.
Phylogenomic databases
eggNOG	arNOG05800.
HOGENOM	HBG553199.
OMA	HQTAGWI.
PhylomeDB	Q2FQM7.
ProtClustDB	CLSK949569.
Enzyme and pathway databases
BioCyc	MHUN323259:MHUN_1008-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_METHJ

Accession

Primary (citable) accession number: Q2FQM7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 21, 2006
Last modified:	November 16, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program