ID   Q2FP12_METHJ            Unreviewed;       808 AA.
AC   Q2FP12;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 87.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:ABD41147.1};
GN   OrderedLocusNames=Mhun_1412 {ECO:0000313|EMBL:ABD41147.1};
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259 {ECO:0000313|EMBL:ABD41147.1, ECO:0000313|Proteomes:UP000001941};
RN   [1] {ECO:0000313|Proteomes:UP000001941}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1
RC   {ECO:0000313|Proteomes:UP000001941};
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000254; ABD41147.1; -; Genomic_DNA.
DR   RefSeq; WP_011448416.1; NC_007796.1.
DR   AlphaFoldDB; Q2FP12; -.
DR   STRING; 323259.Mhun_1412; -.
DR   EnsemblBacteria; ABD41147; ABD41147; Mhun_1412.
DR   GeneID; 25393505; -.
DR   KEGG; mhu:Mhun_1412; -.
DR   eggNOG; arCOG02320; Archaea.
DR   HOGENOM; CLU_000445_107_19_2; -.
DR   InParanoid; Q2FP12; -.
DR   OrthoDB; 8523at2157; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 1.20.120.1530; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR033462; Cache_3-Cache_2.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF17201; Cache_3-Cache_2; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF18947; HAMP_2; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 2.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001941};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          329..382
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          508..744
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   808 AA;  86977 MW;  354D5E46EA5C60DD CRC64;
     MNIRLKITDW LNNATIGKKI TLICLILVII PTLALGFIAY NCAETAIQES LHLNLDTQNE
     DIREATNTVY GLTQGKVNSD LNVLKELFFA KGQPTIINGN MILGSSYKVN DNFEIVDEVQ
     GLLGGAATIF QKKGDQAIRI STNVIGEDGK RAIGTPVAQN VYDAVINKGQ TYYGTAVVVG
     KKYITAYEPI RDQSNDIIGI LFVGVEEKST IGLLEDQIRN KKIGQNGYVF VVDSKGDAII
     HPTEAGKSMN SLPFIQDIIA QKEGYIRYTY QGKEKVASFS YFEPFDWYIV ASAEIEDFLG
     PVEAIRNTII LVVLAGILGG YVVSYLFSRS ISSRMEKLVS LANRVRDGDL SGDDGSSHAK
     DEIGILSRAF SDLITTFLEF RNEIHTISTA ASSGDLNVRG DERKFKGDYA VIINGVNKTV
     DAMAVPLKEA MSLSKKYASG DFRARMRKDL ELQGEFVTFS NALNTIGIDV SQALSAVINQ
     MAHLTGQMKE VSNRVDEVTG ETEEAYKSIE DVSEGTGQVA KIAAAVNDLA DKSGTTTQQI
     LVAMQDLATT VSSVAAKMEH VSELTSTAAE LSEKGKAAAG KADSGMQGIM QASSVIDQMN
     QDISVQMQEI GRIVDIISSI AEETNLLALN AAIEAARAGE AGLGFAVVAA EVKELANESQ
     QSAENIAGII AGLQKKSVAM ADAVQKSIHE VEQGNQAVVQ TLEVFNNIVS SISVINNSMS
     EVAAASEEQA ASVEEVTASV NEFSEMIQQT AKESVGLAAA SQESSAAVDQ ISNMVGQVNE
     SINHIRTSTS EAMDAVHTIE EMMEQFKY
//