ID   Q2FNS1_METHJ            Unreviewed;       862 AA.
AC   Q2FNS1;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=Serine/threonine protein kinase with TPR repeats {ECO:0000313|EMBL:ABD41237.1};
GN   OrderedLocusNames=Mhun_1503 {ECO:0000313|EMBL:ABD41237.1};
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259 {ECO:0000313|EMBL:ABD41237.1, ECO:0000313|Proteomes:UP000001941};
RN   [1] {ECO:0000313|Proteomes:UP000001941}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1
RC   {ECO:0000313|Proteomes:UP000001941};
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000254; ABD41237.1; -; Genomic_DNA.
DR   RefSeq; WP_011448506.1; NC_007796.1.
DR   AlphaFoldDB; Q2FNS1; -.
DR   STRING; 323259.Mhun_1503; -.
DR   EnsemblBacteria; ABD41237; ABD41237; Mhun_1503.
DR   GeneID; 25393518; -.
DR   KEGG; mhu:Mhun_1503; -.
DR   eggNOG; arCOG03042; Archaea.
DR   eggNOG; arCOG03682; Archaea.
DR   HOGENOM; CLU_331945_0_0_2; -.
DR   InParanoid; Q2FNS1; -.
DR   OrthoDB; 115601at2157; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR045269; Atg1-like.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR24348:SF22; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR   PANTHER; PTHR24348; SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED; 1.
DR   Pfam; PF12895; ANAPC3; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SMART; SM00028; TPR; 4.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:ABD41237.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001941};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:ABD41237.1};
KW   Transferase {ECO:0000313|EMBL:ABD41237.1}.
FT   DOMAIN          47..294
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   862 AA;  99905 MW;  E0C06C95C92E4000 CRC64;
     MIPEDVDSPE KRGRTLRDGL SAQFEPSHQA EPDIAGSESQ RYFRTYRIMK QFPATGGEAD
     IWLIQKDRVY YILKHYRLGI EPKIDVLDQV SHISLRNPKN LIKIIDYGFD EDSERWYEIL
     EYARYGSLRD LVQKQSINNN TFKAIIEEIA FGLDTLHKNN VLHLDLKPSN ILIRELRPLN
     LILTDFGIST LLDSELSRHI TTTKGTPMYW APEQLGNVVG RESDYWALGV IALELTEKKH
     PFDGLNHNLI LSTLASRGII LSEQINPDRL ILLKGLLTRN PKKRWGKREV SLWLSGKRNI
     PVYYEEEHTG RMGISKPYEF HDENYYSLHD LMYAFIGDPV SWEDAKRHIG RGYLLRWLEA
     TEQYNKAVTI SKYIETYPNE DERLLYIAAE LNRDIPFTLF GKVIDITNIV WFLGRSLNRE
     QDENEERIII MLFSGEIEEM YTKFLEITKQ EVKSIFFMRL FAWIKSNPRG TNERKRLFQY
     AKILHERELA GIPTEWSAKS VIAIVSIYQN FIKLSAKSDA DECKKDMIAA AKHALAAQVI
     EPDLLVALAS AFEELQDEKS GKLLLKKAYN LDIRVLTLLF NKRKGLPRFR FYTALTREYE
     KNLISISSDP WNETATFWKE KYVQYYLEDN FSLALSISER LIEMDKAGAV GWAMRGVSLF
     KLKRSHEAGF CLSHKVIQTS DDPFITWLTG EHLEETGNPA LAEQKYLQVP IVHIAQPVPQ
     IGLARLYFKQ KRYWESIEIC DKILATYPGL PKALFYKGES LYAIERVPEA LQSFLDICNN
     HPDHLQSCVK AARCYLKLGD YTEADKYITG VIEKDETIIE ALRIKVFILL KRGAKAEARL
     YLDKILVIDP ENEWAQRMLA IK
//