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Protein

ORC1-type DNA replication protein

Gene

cdc6

Organism
Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in regulation of DNA replication.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei226 – 2261ATPUniRule annotation
Binding sitei238 – 2381ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi71 – 755ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA replication

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMHUN323259:GH0L-2504-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
ORC1-type DNA replication proteinUniRule annotation
Gene namesi
Name:cdc6
Ordered Locus Names:Mhun_2471
OrganismiMethanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Taxonomic identifieri323259 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanospirillaceaeMethanospirillum
Proteomesi
  • UP000001941 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 424424ORC1-type DNA replication proteinPRO_0000307416Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi323259.Mhun_2471.

Structurei

3D structure databases

ProteinModelPortaliQ2FN79.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CDC6/cdc18 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00467. Archaea.
COG1474. LUCA.
HOGENOMiHOG000230140.
KOiK10725.
OMAiTGWPTDQ.

Family and domain databases

CDDicd08768. Cdc6_C. 1 hit.
Gene3Di1.10.10.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01407. ORC1_type_DNA_replic_protein. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR015163. Cdc6_C.
IPR014277. Orc1/Cdc6_arc.
IPR027417. P-loop_NTPase.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF13401. AAA_22. 1 hit.
PF09079. Cdc6_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM01074. Cdc6_C. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02928. TIGR02928. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2FN79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQDMNDSPG LFDKYLSENR IFRDREVLRH SYRPHILPHR KPQIDQIAAI
60 70 80 90 100
LAPALQTETP SNILIYGKTG TGKTASVRYV GSELESVSAR RGTVCRVIHL
110 120 130 140 150
NCEVIDTQYR VLAQISKLIM GEDETPSDKI KTHIPMTGWP TDQVYSELKN
160 170 180 190 200
QIELNSGVFI IILDEIDKLV KKSGDDTLYN LTRINTDLNR SKVSIIGISN
210 220 230 240 250
DLGFKTFLDP RVLSSLSEEE LVFPPYNAPQ LCDILQQRAV IGFAEDALED
260 270 280 290 300
EVIPLCAALA AQEHGDARRA LDLLRISGEL ADRENGSKVT VEHVKKAQAK
310 320 330 340 350
IETDSMVECI RTLPTQSKIV LYCMLLLHRA GQRIFISGDV TRIYKELTPF
360 370 380 390 400
LEIDVLTARR ISDLISELNM LGVINTRLVN RGRHGRTKEM WFDTNTDKIW
410 420
EVIMEESDGR LAQVDEQIVV QILR
Length:424
Mass (Da):47,966
Last modified:March 21, 2006 - v1
Checksum:i6F51847C58226BCD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000254 Genomic DNA. Translation: ABD42171.1.
RefSeqiWP_011449429.1. NC_007796.1.

Genome annotation databases

EnsemblBacteriaiABD42171; ABD42171; Mhun_2471.
GeneIDi3923976.
KEGGimhu:Mhun_2471.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000254 Genomic DNA. Translation: ABD42171.1.
RefSeqiWP_011449429.1. NC_007796.1.

3D structure databases

ProteinModelPortaliQ2FN79.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi323259.Mhun_2471.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD42171; ABD42171; Mhun_2471.
GeneIDi3923976.
KEGGimhu:Mhun_2471.

Phylogenomic databases

eggNOGiarCOG00467. Archaea.
COG1474. LUCA.
HOGENOMiHOG000230140.
KOiK10725.
OMAiTGWPTDQ.

Enzyme and pathway databases

BioCyciMHUN323259:GH0L-2504-MONOMER.

Family and domain databases

CDDicd08768. Cdc6_C. 1 hit.
Gene3Di1.10.10.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01407. ORC1_type_DNA_replic_protein. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR015163. Cdc6_C.
IPR014277. Orc1/Cdc6_arc.
IPR027417. P-loop_NTPase.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF13401. AAA_22. 1 hit.
PF09079. Cdc6_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM01074. Cdc6_C. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02928. TIGR02928. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCDC6_METHJ
AccessioniPrimary (citable) accession number: Q2FN79
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: March 21, 2006
Last modified: September 7, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.