Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei160GTPUniRule annotation1
Binding sitei163GTPUniRule annotation1
Binding sitei206GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi42 – 46GTPUniRule annotation5
Nucleotide bindingi129 – 131GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMHUN323259:G1G5Z-999-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Mhun_0942Imported
OrganismiMethanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)Imported
Taxonomic identifieri323259 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanospirillaceaeMethanospirillum
Proteomesi
  • UP000001941 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Protein-protein interaction databases

STRINGi323259.Mhun_0942

Structurei

3D structure databases

ProteinModelPortaliQ2FN53
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 224TubulinInterPro annotationAdd BLAST191
Domaini226 – 343Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG02201 Archaea
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiIMNQGGV
OrthoDBiPOG093Z0942

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q2FN53-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSIINAAVI NAEREKELKN ISQNYDDDID GQPRIVIIGC GGAGNNTINR
60 70 80 90 100
LHHMGVSGAE TIAINTDKQH LDMIQADKRI LIGKSLTKGL GAGGYPEIGR
110 120 130 140 150
KAAEMARPTL ESLLESVDLC FITAGMGGGT GTGSAPAVAQ IAKEQGAIVV
160 170 180 190 200
GMVSYPFDVE KARLIRAEDG LEAMSKACDS VILLDNNRLK SFVPNLPLAQ
210 220 230 240 250
SFSVMDQLIG ETVKGITETI TEPSLINIDY ADVRAIMSKG GVATMLVGES
260 270 280 290 300
KQQNKAESVV RECLSNPMLD IDYRGATGAL IHITGGSDLT LIESEEIASS
310 320 330 340 350
LTYELDPHAD VIWGARIRSD MEGKVRVLAI MTGVKNGDTI AKPKQPYKEK
360 370 380
LDRIEEQIRY PKSPDLARIK PRSVTAAMDY ASGPDIMWM
Length:389
Mass (Da):41,899
Last modified:March 21, 2006 - v1
Checksum:i2AA16B07F41C3FC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000254 Genomic DNA Translation: ABD40692.1
RefSeqiWP_011447971.1, NC_007796.1

Genome annotation databases

EnsemblBacteriaiABD40692; ABD40692; Mhun_0942
GeneIDi3923064
KEGGimhu:Mhun_0942

Similar proteinsi

Entry informationi

Entry nameiQ2FN53_METHJ
AccessioniPrimary (citable) accession number: Q2FN53
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health