ID   Q2FMI7_METHJ            Unreviewed;       706 AA.
AC   Q2FMI7;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   SubName: Full=Serine phosphatase {ECO:0000313|EMBL:ABD39838.1};
GN   OrderedLocusNames=Mhun_0060 {ECO:0000313|EMBL:ABD39838.1};
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259 {ECO:0000313|EMBL:ABD39838.1, ECO:0000313|Proteomes:UP000001941};
RN   [1] {ECO:0000313|Proteomes:UP000001941}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1
RC   {ECO:0000313|Proteomes:UP000001941};
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP000254; ABD39838.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2FMI7; -.
DR   STRING; 323259.Mhun_0060; -.
DR   EnsemblBacteria; ABD39838; ABD39838; Mhun_0060.
DR   KEGG; mhu:Mhun_0060; -.
DR   eggNOG; arCOG02362; Archaea.
DR   eggNOG; arCOG06893; Archaea.
DR   HOGENOM; CLU_020306_1_0_2; -.
DR   InParanoid; Q2FMI7; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001941};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        380..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          401..453
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          491..705
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
SQ   SEQUENCE   706 AA;  77893 MW;  17C400ACBF3E5A00 CRC64;
     MKRMRIGVAG KLLLIMVLLT SLIFIIIGGI SWIVMGNLGA YATQSSLALG EQAIGESTTA
     LEEDAEIYLL RLVKDQAEIT DMVFERIISE MNVLNDYGKV MIKENNVTPV TWYTRDIKPA
     KPGETGIIHL SPGVTAEHVL DEIMALSSFQ PVFNTLFHAD NRLTALYVTS SSGITFIFPW
     TPRVDPTFEP RSRSWFLEAV NSSQFVWSDP YVDVLGNGLT ITCSKAVHSP DKTRTWVIGS
     DITIETINYR IITTQLGEDG YAFLINQRGD ILSRPGLSAG ETRWDKSYET ENLLQSTNED
     LRKVAEEMTR GLSGVSRCRF AEGDKYIAYA PVKSVGWSIG LVVPVEQVIG PAHITGSVIR
     LASEETHSHI TEQMSFLQKI LITSFFLLFI GVTGIAIFFS KIITGPVMIL SEGARRIGNG
     DLQTPVEIHT GDEFEELAGA FNRMTNDLRN YIVELRRTTA EKERFTRELE IAQGIQQSFL
     PDNVPDIPGM ELAVFSSPAL EVGGDFYDFI PVGDDQWGLV IADVSGKGVP AALFMALSRT
     LIRVSATWKS SPASAITEAN TLICRDSKAS MFVTLFYLVI DSKKRQITYV NAGHNPPLML
     TGGDQSDITL LKAEGIALGI IDDIDLASVT VDLKKGDMVA LYTDGITEAM NKDGEEYGIE
     RFTEVLMQNR DLDLSALINA IKTSIKEFTK DAPQSDDITL ILFRAV
//