ID   Q2FLA5_METHJ            Unreviewed;       814 AA.
AC   Q2FLA5;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 87.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:ABD40124.1};
GN   OrderedLocusNames=Mhun_0354 {ECO:0000313|EMBL:ABD40124.1};
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259 {ECO:0000313|EMBL:ABD40124.1, ECO:0000313|Proteomes:UP000001941};
RN   [1] {ECO:0000313|Proteomes:UP000001941}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1
RC   {ECO:0000313|Proteomes:UP000001941};
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000254; ABD40124.1; -; Genomic_DNA.
DR   RefSeq; WP_011447418.1; NC_007796.1.
DR   AlphaFoldDB; Q2FLA5; -.
DR   STRING; 323259.Mhun_0354; -.
DR   EnsemblBacteria; ABD40124; ABD40124; Mhun_0354.
DR   GeneID; 3922532; -.
DR   KEGG; mhu:Mhun_0354; -.
DR   eggNOG; arCOG02320; Archaea.
DR   HOGENOM; CLU_000445_107_19_2; -.
DR   InParanoid; Q2FLA5; -.
DR   OrthoDB; 342253at2157; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd12913; PDC1_MCP_like; 1.
DR   Gene3D; 1.20.120.1530; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF18947; HAMP_2; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 3.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001941};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        14..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..348
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          350..402
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          528..764
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   814 AA;  87227 MW;  2C0590AF6BE6EC11 CRC64;
     MVSLFSVSSI NKKILYAGSL SLLVVASVII LFAAFSTYNT SVSGAEDELK ILADAQAEAI
     KGVLLEPMHS TESLAEVLLG PYSAGKPLPR EEVESIIGGI LKNHPLYNGV YTMWEENAYD
     RADSRYAGKN GFSSTGRMNM YWYREDGVEQ RMIYEPDSVD TETDYTQDYY TIPAQTHQKL
     LTNPYVEPSQ SVPVLMASTI VPILSQGTFL GITGVDVTLA DIDRIADETR LYNGEGIVLI
     VSNDGTIAGV TGDIGTVGEP LTSLAPVFSV SEETIQHIIT GESDATFTLG PYVGKMSDVV
     VGDPGLPWKV LVLVPSSILT ANAISLTIIL VIFGILISAG GVGLLYIVAR SISRPIQEIT
     YAAGRLAEGD LSCRINPDGH DEVAILGRTF DTMASRLQQT MNTITRDGED QKAVLAEING
     IAQAASNGDL NVRGDPAHFS GEYRHVIEAV NDTLDAVVRP VTEAMTLARE YSAGNFSARF
     DPGVPVSGDF IHFRTALDTI GIQMGSLIGA LSNEVQGLMT EMEESNASVE EIASASQAIA
     RGTNELSIQA DLSKSEITKI QDTVSSVISI GSDIANQTAE ASVLINQSQQ LSHKGSESST
     LADIGMKSIV KSHDETGRII HEINSEMDKI GDIVGIITDI ADQTNLLALN AAIEAARAGD
     AGKGFAVVAG EVKALALESQ KSAEKISGII SLLQERSAKM KSAIDTSRQD VNNGSRAVDE
     TLKIFSELAS SIDEITKRIV SIDSASQDQM AAYEMVMEHI TSMNESFHTI INELGNTAAL
     TEENSVSLDC IAQSIQEATI RIDKISRDMS RFRV
//