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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Staphylococcus aureus (strain USA300)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi30 – 378ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair, DNA replication, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSAUR451515:GH3C-4-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:SAUSA300_0004
OrganismiStaphylococcus aureus (strain USA300)
Taxonomic identifieri367830 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000001939 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 370370DNA replication and repair protein RecFPRO_0000236148Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ2FKQ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000269559.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiEOG6HTP3X.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2FKQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNTLQLEN YRNYDEVTLK CHPDVNILIG ENAQGKTNLL ESIYTLALAK
60 70 80 90 100
SHRTSNDKEL IRFNADYAKI EGELSYRHGT MPLTMFITKK GKQVKVNHLE
110 120 130 140 150
QSRLTQYIGH LNVVLFAPED LNIVKGSPQI RRRFIDMELG QISAVYLNDL
160 170 180 190 200
AQYQRILKQK NNYLKQLQLG QKKDLTMLEV LNQQFAEYAM KVTDKRAHFI
210 220 230 240 250
QELESLAKPI HAGITNDKEA LSLNYLPSLK FDYAQNEAAR LEEIMSILSD
260 270 280 290 300
NMQREKERGI SLFGPHRDDI SFDVNGMDAQ TYGSQGQQRT TALSIKLAEI
310 320 330 340 350
ELMNIEVGEY PILLLDDVLS ELDDSRQTHL LSTIQHKVQT FVTTTSVDGI
360 370
DHEIMNNPKL YRINQGEIIK
Length:370
Mass (Da):42,441
Last modified:March 21, 2006 - v1
Checksum:i2D6471A95D2E1368
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000255 Genomic DNA. Translation: ABD22345.1.

Genome annotation databases

EnsemblBacteriaiABD22345; ABD22345; SAUSA300_0004.
KEGGisaa:SAUSA300_0004.
PATRICi19589216. VBIStaAur129981_0051.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000255 Genomic DNA. Translation: ABD22345.1.

3D structure databases

ProteinModelPortaliQ2FKQ2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD22345; ABD22345; SAUSA300_0004.
KEGGisaa:SAUSA300_0004.
PATRICi19589216. VBIStaAur129981_0051.

Phylogenomic databases

HOGENOMiHOG000269559.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiEOG6HTP3X.

Enzyme and pathway databases

BioCyciSAUR451515:GH3C-4-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus."
    Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G., Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F., Perdreau-Remington F.
    Lancet 367:731-739(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ANTIBIOTIC RESISTANCE.
    Strain: USA300.

Entry informationi

Entry nameiRECF_STAA3
AccessioniPrimary (citable) accession number: Q2FKQ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: March 21, 2006
Last modified: April 13, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.