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Q2FK94

- ALDA_STAA3

UniProt

Q2FK94 - ALDA_STAA3

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Protein

Putative aldehyde dehydrogenase AldA

Gene

aldA

Organism
Staphylococcus aureus (strain USA300)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei256 – 2561By similarity
Active sitei290 – 2901By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi212 – 2187NADBy similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciSAUR451515:GH3C-170-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase AldA (EC:1.2.1.3)
Gene namesi
Name:aldA
Ordered Locus Names:SAUSA300_0170
OrganismiStaphylococcus aureus (strain USA300)
Taxonomic identifieri367830 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001939: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 495495Putative aldehyde dehydrogenase AldAPRO_0000290789Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi451515.SAUSA300_0170.

Structurei

3D structure databases

ProteinModelPortaliQ2FK94.
SMRiQ2FK94. Positions 13-487.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271505.
KOiK00128.
OMAiHDQFVER.
OrthoDBiEOG6BS8QW.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2FK94-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVNVRDYIA ENYGLFINGE FVKGSSDETI EVTNPATGET LSHITRAKDK
60 70 80 90 100
DVDHAVKVAQ EAFESWSLTS KSERAQMLRD IGDKLMAQKD KIAMIETLNN
110 120 130 140 150
GKPIRETTAI DIPFAARHFH YFASVIETEE GTVNDIDKDT MSIVRHEPIG
160 170 180 190 200
VVGAVVAWNF PMLLAAWKIA PAIAAGNTIV IQPSSSTPLS LLEVAKIFQE
210 220 230 240 250
VLPKGVVNIL TGKGSESGNA IFNHDGVDKL SFTGSTDVGY QVAEAAAKHL
260 270 280 290 300
VPATLELGGK SANIILDDAN LDLAVEGIQL GILFNQGEVC SAGSRLLVHE
310 320 330 340 350
KIYDQLVPRL QEAFSNIKVG NPQDEATQMG SQTGKDQLDK IQSYIDAAKE
360 370 380 390 400
SDAQILAGGH RLTENGLDKG FFFEPTLIAV PDNHHKLAQE EIFGPVLTVI
410 420 430 440 450
KVKDDQEAID IANDSEYGLA GGVFSQNITR ALNIAKAVRT GRIWINTYNQ
460 470 480 490
VPEGAPFGGY KKSGIGRETY KGALSNYQQV KNIYIDTSNA LKGLY
Length:495
Mass (Da):53,659
Last modified:March 21, 2006 - v1
Checksum:iDCBE4F433645A52A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000255 Genomic DNA. Translation: ABD21998.1.
RefSeqiYP_492884.1. NC_007793.1.

Genome annotation databases

EnsemblBacteriaiABD21998; ABD21998; SAUSA300_0170.
GeneIDi3913223.
KEGGisaa:SAUSA300_0170.
PATRICi19589578. VBIStaAur129981_0229.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000255 Genomic DNA. Translation: ABD21998.1 .
RefSeqi YP_492884.1. NC_007793.1.

3D structure databases

ProteinModelPortali Q2FK94.
SMRi Q2FK94. Positions 13-487.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 451515.SAUSA300_0170.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD21998 ; ABD21998 ; SAUSA300_0170 .
GeneIDi 3913223.
KEGGi saa:SAUSA300_0170.
PATRICi 19589578. VBIStaAur129981_0229.

Phylogenomic databases

eggNOGi COG1012.
HOGENOMi HOG000271505.
KOi K00128.
OMAi HDQFVER.
OrthoDBi EOG6BS8QW.

Enzyme and pathway databases

BioCyci SAUR451515:GH3C-170-MONOMER.

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
SUPFAMi SSF53720. SSF53720. 1 hit.
PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus."
    Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G., Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F., Perdreau-Remington F.
    Lancet 367:731-739(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USA300.

Entry informationi

Entry nameiALDA_STAA3
AccessioniPrimary (citable) accession number: Q2FK94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: March 21, 2006
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3