Q2FK19 (Q2FK19_STAA3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase RuleBase RU003490
EC=2.7.7.60 RuleBase RU003490

Gene names

Ordered Locus Names:

SAUSA300_0245

Organism

Staphylococcus aureus (strain USA300) [Complete proteome] [HAMAP]

Taxonomic identifier

367830 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	224 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) By similarity. RuleBase RU003490 SAAS SAAS018294
Catalytic activity	CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol. RuleBase RU003490 SAAS SAAS018294
Pathway	Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6. SAAS SAAS018294
Sequence similarities	Belongs to the IspD family. RuleBase RU004393

Ontologies

Keywords
Biological process	Isoprene biosynthesis SAAS SAAS018294 RuleBase RU004393
Molecular function	Nucleotidyltransferase SAAS SAAS018294 RuleBase RU004393 EMBL ABD21756.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	isoprenoid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2FK19 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: 3A9FA08E512457A1	FASTA	224	25,214
	10 20 30 40 50 60 MGNVPLPKQF LDIDNKPILI HTIEKFILVS EFNEIIIATP AQWISHTQDI LKKYNITDQR 70 80 90 100 110 120 VKVVAGGTDR NETIMNIIDH IRNVNGINND DVIVTHDAVR PFLTQRIIKE NIEVAAKYGA 130 140 150 160 170 180 VDTVIEAIDT IVMSKDKQNI HSIPVRNEMY QGQTPQSFNI KLLQDSYRAL SSEQKEILSD 190 200 210 220 ACKIIVESGH AVKLVRGELY NIKVTTPYDL KVANAIIQGD IADD

References

[1]

"Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus." Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G., Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F., Perdreau-Remington F. Lancet 367:731-739(2006) [PubMed: 16517273] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000255 Genomic DNA. Translation: ABD21756.1.
RefSeq	YP_492959.1. NC_007793.1.
3D structure databases
ProteinModelPortal	Q2FK19.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000037901; EBSTAP00000036609; EBSTAG00000037899.
GeneID	3915239.
GenomeReviews	Gene locus SAUSA300_0245 in contig CP000255_GR.
KEGG	saa:SAUSA300_0245.
PATRIC	19589732. VBIStaAur129981_0306.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1211.
GeneTree	EBGT00050000024510.
HOGENOM	HBG672839.
OMA	GELFNIK.
ProtClustDB	PRK13385.
Family and domain databases
InterPro	IPR001228. ISPD_synthase. IPR018294. ISPD_synthase_CS. [Graphical view]
KO	K00991.
Pfam	PF01128. IspD. 1 hit. [Graphical view]
PROSITE	PS01295. ISPD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2FK19_STAA3

Accession

Primary (citable) accession number: Q2FK19

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)