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Reviewed, UniProtKB/Swiss-Prot Q2FJU6 (NANE_STAA3)

Last modified June 16, 2009. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Putative N-acetylmannosamine-6-phosphate 2-epimerase
    EC=5.1.3.9
Alternative name(s):
    ManNAc-6-P epimerase
Gene names
Name: nanE
Ordered Locus Names: SAUSA300_0318
OrganismStaphylococcus aureus (strain USA300) [Complete proteome] [HAMAP]
Taxonomic identifier367830 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesStaphylococcus

Protein attributes

Sequence length222 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) Potential.

Catalytic activity

N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate. HAMAP MF_01235

Pathway

Amino-sugar metabolism; N-acetylneuraminic acid degradation; D-fructose 6-phosphate from N-acetylneuraminic acid: step 3/5. HAMAP MF_01235

Sequence similarities

Belongs to the nanE family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processN-acetylmannosamine metabolic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionN-acylglucosamine-6-phosphate 2-epimerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 222222Putative N-acetylmannosamine-6-phosphate 2-epimerase HAMAP MF_01235
PRO_0000301486

Sequences

Sequence LengthMass (Da)Tools
Q2FJU6-1 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: 7417D8DD1A48A041

FASTA22224,545
        10         20         30         40         50         60 
MLPHGLIVSC QALPDEPLHS SFIMSKMALA AYEGGAVGIR ANTKEDILAI KETVDLPVIG 

        70         80         90        100        110        120 
IVKRDYDHSD VFITATSKEV DELIESQCEV IALDATLQQR PKETLDELVS YIRTHAPNVE 

       130        140        150        160        170        180 
IMADIATVEE AKNAARLGFD YIGTTLHGYT SYTQGQLLYQ NDFQFLKDVL QSVDAKVIAE 

       190        200        210        220 
GNVITPDMYK RVMDLGVHCS VVGGAITRPK EITKRFVQIM ED 

« Hide

References

[1]"Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus."
Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G., Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F., Perdreau-Remington F.
Lancet 367:731-739(2006) [PubMed: 16517273] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000255 Genomic DNA. Translation: ABD21297.1.
RefSeqYP_493032.1.

3D structure databases

SMRQ2FJU6. Positions 1-221.
ModBaseSearch...

Genome annotation databases

GeneID3913041.
GenomeReviewsGene locus SAUSA300_0318 in contig CP000255_GR.
KEGGsaa:SAUSA300_0318.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ2FJU6.
OMAQ2FJU6. YNTPELA.

Family and domain databases

HAMAPMF_01235.
[Tree]
InterProIPR007260. NanE.
[Graphical view]
PfamPF04131. NanE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNANE_STAA3
AccessionPrimary (citable) accession number: Q2FJU6
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 21, 2006
Last modified: June 16, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents