Reviewed,
UniProtKB/Swiss-Prot Q2FJH7 (SLE1_STAA3)
Last modified
January 19, 2010.
Version 30.
History...
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90%,
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: N-acetylmuramoyl-L-alanine amidase sle1 EC=3.5.1.28 | ||||||
| Gene names |
| ||||||
| Organism | Staphylococcus aureus (strain USA300) [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 367830 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Staphylococcus |
Protein attributes
| Sequence length | 334 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Peptidoglycan hydrolase involved in the splitting of the septum during cell division By similarity. |
| Catalytic activity | Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. |
| Subcellular location | Secreted By similarity. Cell surface By similarity. |
| Sequence similarities | Contains 3 LysM repeats. Contains 1 peptidase C51 domain. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 25 | 25 | Potential | ||||||
| Chain | 26 – 334 | 309 | N-acetylmuramoyl-L-alanine amidase sle1 | PRO_0000271076 | |||||
Regions | |||||||||
| Repeat | 29 – 71 | 43 | LysM 1 | ||||||
| Repeat | 93 – 135 | 43 | LysM 2 | ||||||
| Repeat | 160 – 202 | 43 | LysM 3 | ||||||
| Domain | 210 – 334 | 125 | Peptidase C51 | ||||||
Sequences
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References
| [1] | "Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus." Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G., Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F., Perdreau-Remington F. Lancet 367:731-739(2006) [PubMed: 16517273] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000255 Genomic DNA. Translation: ABD20550.1. |
| RefSeq | YP_493151.1. |
3D structure databases | |
| SMR | Q2FJH7. Positions 26-72, 92-189, 206-334. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q2FJH7. |
Genome annotation databases | |
| GeneID | 3912915. |
| GenomeReviews | Gene locus SAUSA300_0438 in contig CP000255_GR. |
| KEGG | saa:SAUSA300_0438. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG1388. |
| HOGENOM | HBG697363. |
| OMA | FNIYPGQ. |
Family and domain databases | |
| InterPro | IPR007921. CHAP. IPR018392. Peptidoglycan-bd_lysin. IPR002482. Peptidoglycan-bd_Lysin_sg. [Graphical view] |
| Pfam | PF05257. CHAP. 1 hit. PF01476. LysM. 3 hits. [Graphical view] |
| SMART | SM00257. LysM. 3 hits. [Graphical view] |
| PROSITE | PS50911. CHAP. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | SLE1_STAA3 | ||||||||
| Accession | Primary (citable) accession number: Q2FJH7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Peptidase families Classification of peptidase families and list of entries |
| SIMILARITY comments Index of protein domains and families |

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