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Q2FJE1 (Q2FJE1_STAA3) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribose-phosphate pyrophosphokinase HAMAP-Rule MF_00583
Short name=RPPK HAMAP-Rule MF_00583
EC=2.7.6.1 HAMAP-Rule MF_00583
Alternative name(s):
Phosphoribosyl pyrophosphate synthase HAMAP-Rule MF_00583
Gene names
Name:prs HAMAP-Rule MF_00583 EMBL ABD22019.1
Ordered Locus Names:SAUSA300_0478 EMBL ABD22019.1
OrganismStaphylococcus aureus (strain USA300) [Complete proteome] [HAMAP]
Taxonomic identifier367830 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus ›

Protein attributes

Sequence length321 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00583 RuleBase RU004325

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_00583

Pathway

Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1. HAMAP-Rule MF_00583

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00583.

Sequence similarities

Belongs to the ribose-phosphate pyrophosphokinase family. HAMAP-Rule MF_00583 RuleBase RU004324

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region221 – 234145-phosphoribose 1-diphosphate binding By similarity HAMAP-Rule MF_00583

Sites

Metal binding1351Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1371Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1461Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1501Magnesium By similarity HAMAP-Rule MF_00583

Sequences

Sequence LengthMass (Da)Tools
Q2FJE1 [UniParc].

Last modified March 21, 2006. Version 1.
Checksum: 70A955AA62C9415E

FASTA32135,284
        10         20         30         40         50         60 
MLNNEYKNSS LKIFSLKGNE ALAQEVADQV GIELGKCSVK RFSDGEIQIN IEESIRGCDV 

        70         80         90        100        110        120 
FIIQPTSYPV NLHLMELLIM IDACKRASAA TINIVVPYYG YARQDRKARS REPITAKLVA 

       130        140        150        160        170        180 
NLIETAGATR MIALDLHAPQ IQGFFDIPID HLMGVPILAK HFKDDPNINP EECVVVSPDH 

       190        200        210        220        230        240 
GGVTRARKLA DILKTPIAII DKRRPRPNVA EVMNIVGEIE GRTAIIIDDI IDTAGTITLA 

       250        260        270        280        290        300 
AQALKDKGAK EVYACCTHPV LSGPAKERIE NSAIKELIVT NSIHLDEDRK PSNTKELSVA 

       310        320 
GLIAQAIIRV YERESVSVLF D

« Hide

References

[1]"Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus."
Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G., Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F., Perdreau-Remington F.
Lancet 367:731-739(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USA300.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000255 Genomic DNA. Translation: ABD22019.1.
RefSeqYP_493187.1. NC_007793.1.

3D structure databases

ProteinModelPortalQ2FJE1.
SMRQ2FJE1. Positions 10-320.
ModBaseSearch...

Protein-protein interaction databases

STRING451515.SAUSA300_0478.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD22019; ABD22019; SAUSA300_0478.
GeneID3913205.
KEGGsaa:SAUSA300_0478.
PATRIC19590220. VBIStaAur129981_0546.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000210449.
KOK00948.
OMAYVQIQES.
ProtClustDBPRK01259.

Enzyme and pathway databases

BioCycSAUR451515:GH3C-478-MONOMER.
UniPathwayUPA00087; UER00172.

Family and domain databases

HAMAPMF_00583_B. RibP_PPkinase_B.
InterProIPR000842. PRib_PP_synth_CS.
IPR000836. PRibTrfase_dom.
IPR005946. Rib-P_diPkinase.
[Graphical view]
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR01251. ribP_PPkin. 1 hit.
PROSITEPS00114. PRPP_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2FJE1_STAA3
AccessionPrimary (citable) accession number: Q2FJE1
Entry history
Integrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: May 29, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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