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Protein
Submitted name:

Thiamine pyrophosphokinase

Gene

SAUSA300_1116

Organism
Staphylococcus aureus (strain USA300)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. kinase activity Source: UniProtKB-KW
  3. thiamine binding Source: InterPro
  4. thiamine diphosphokinase activity Source: UniProtKB-EC

GO - Biological processi

  1. thiamine diphosphate biosynthetic process Source: InterPro
  2. thiamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

BioCyciSAUR451515:GH3C-1116-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Thiamine pyrophosphokinaseImported (EC:2.7.6.2Imported)
Gene namesi
Ordered Locus Names:SAUSA300_1116Imported
OrganismiStaphylococcus aureus (strain USA300)Imported
Taxonomic identifieri367830 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001939: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi451515.SAUSA300_1116.

Structurei

3D structure databases

ProteinModelPortaliQ2FHL5.
SMRiQ2FHL5. Positions 1-211.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000037072.
KOiK00949.
OMAiITYCPEG.
OrthoDBiEOG62NX6M.

Family and domain databases

Gene3Di2.60.120.320. 1 hit.
3.40.50.10240. 1 hit.
InterProiIPR006282. Thi_PPkinase.
IPR007373. Thiamin_PyroPKinase_B1-bd.
IPR007371. TPK_catalytic.
[Graphical view]
PfamiPF04265. TPK_B1_binding. 1 hit.
PF04263. TPK_catalytic. 1 hit.
[Graphical view]
SMARTiSM00983. TPK_B1_binding. 1 hit.
[Graphical view]
SUPFAMiSSF63862. SSF63862. 1 hit.
SSF63999. SSF63999. 1 hit.
TIGRFAMsiTIGR01378. thi_PPkinase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2FHL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHINLLCSDR HLPQDIWAKS NEGKWGGVDR GALILLKHQI IPFFSVGDFD
60 70 80 90 100
SVSKEERQLL TEQLQIKPVQ AEKADTDLAL AVDKAVALGF DSITIYGATG
110 120 130 140 150
GRLDHFFGAI QLLLKKAYYK HDVHIEVIDQ QNKIELLPKG QHTVEKDKSY
160 170 180 190 200
PYISFIPMTD DVELSLAGFK YNLARQMLNI GSTLTISNEI ESLQAKVTVH
210
DGLILQIRST DLN
Length:213
Mass (Da):23,884
Last modified:March 21, 2006 - v1
Checksum:i6D409D57EC96D182
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000255 Genomic DNA. Translation: ABD21455.1.
RefSeqiYP_493813.1. NC_007793.1.

Genome annotation databases

EnsemblBacteriaiABD21455; ABD21455; SAUSA300_1116.
GeneIDi3915362.
KEGGisaa:SAUSA300_1116.
PATRICi19591599. VBIStaAur129981_1227.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000255 Genomic DNA. Translation: ABD21455.1.
RefSeqiYP_493813.1. NC_007793.1.

3D structure databases

ProteinModelPortaliQ2FHL5.
SMRiQ2FHL5. Positions 1-211.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi451515.SAUSA300_1116.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD21455; ABD21455; SAUSA300_1116.
GeneIDi3915362.
KEGGisaa:SAUSA300_1116.
PATRICi19591599. VBIStaAur129981_1227.

Phylogenomic databases

HOGENOMiHOG000037072.
KOiK00949.
OMAiITYCPEG.
OrthoDBiEOG62NX6M.

Enzyme and pathway databases

BioCyciSAUR451515:GH3C-1116-MONOMER.

Family and domain databases

Gene3Di2.60.120.320. 1 hit.
3.40.50.10240. 1 hit.
InterProiIPR006282. Thi_PPkinase.
IPR007373. Thiamin_PyroPKinase_B1-bd.
IPR007371. TPK_catalytic.
[Graphical view]
PfamiPF04265. TPK_B1_binding. 1 hit.
PF04263. TPK_catalytic. 1 hit.
[Graphical view]
SMARTiSM00983. TPK_B1_binding. 1 hit.
[Graphical view]
SUPFAMiSSF63862. SSF63862. 1 hit.
SSF63999. SSF63999. 1 hit.
TIGRFAMsiTIGR01378. thi_PPkinase. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus."
    Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G., Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F., Perdreau-Remington F.
    Lancet 367:731-739(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USA300Imported.

Entry informationi

Entry nameiQ2FHL5_STAA3
AccessioniPrimary (citable) accession number: Q2FHL5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: January 7, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.