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Q2FHD8

- GLPD_STAA3

UniProt

Q2FHD8 - GLPD_STAA3

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Protein

Aerobic glycerol-3-phosphate dehydrogenase

Gene

glpD

Organism
Staphylococcus aureus (strain USA300)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactori

FAD.By similarity

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 4929FADSequence AnalysisAdd
BLAST

GO - Molecular functioni

  1. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycerol-3-phosphate metabolic process Source: InterPro
  2. glycerol catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Glycerol metabolism

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciSAUR451515:GH3C-1193-MONOMER.
UniPathwayiUPA00618; UER00674.

Names & Taxonomyi

Protein namesi
Recommended name:
Aerobic glycerol-3-phosphate dehydrogenase (EC:1.1.5.3)
Gene namesi
Name:glpD
Ordered Locus Names:SAUSA300_1193
OrganismiStaphylococcus aureus (strain USA300)
Taxonomic identifieri367830 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001939: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 557557Aerobic glycerol-3-phosphate dehydrogenasePRO_0000270056Add
BLAST

Proteomic databases

PRIDEiQ2FHD8.

Interactioni

Protein-protein interaction databases

STRINGi451515.SAUSA300_1193.

Structurei

3D structure databases

ProteinModelPortaliQ2FHD8.
SMRiQ2FHD8. Positions 3-546.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004812.
KOiK00111.
OMAiNDIEASW.
OrthoDBiEOG651SR7.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2FHD8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALSTFKREH IKKNLRNDEY DLVIIGGGIT GAGIALDASE RGMKVALVEM
60 70 80 90 100
QDFAQGTSSR STKLVHGGLR YLKQFQIGVV AETGKERAIV YENGPHVTTP
110 120 130 140 150
EWMLLPMHKG GTFGKFSTSI GLGMYDRLAG VKKSERKKML SKKETLAKEP
160 170 180 190 200
LVKKEGLKGG GYYVEYRTDD ARLTIEVMKR AAEKGAEIIN YTKSEHFTYD
210 220 230 240 250
KNQQVNGVKV IDKLTNENYT IKAKKVVNAA GPWVDDVRSG DYARNNKKLR
260 270 280 290 300
LTKGVHVVID QSKFPLGQAV YFDTEKDGRM IFAIPREGKA YVGTTDTFYD
310 320 330 340 350
NIKSSPLTTQ EDRDYLIDAI NYMFPSVNVT DEDIESTWAG IRPLIYEEGK
360 370 380 390 400
DPSEISRKDE IWEGKSGLLT IAGGKLTGYR HMAQDIVDLV SKRLKKDYGL
410 420 430 440 450
TFSPCNTKGL AISGGDVGGS KNFDAFVEQK VDVAKGFGID EDVARRLASK
460 470 480 490 500
YGSNVDELFN IAQTSQYHDS KLPLEIYVEL VYSIQQEMVY KPNDFLVRRS
510 520 530 540 550
GKMYFNIKDV LDYKDAVIDI MADMLDYSPA QIEAYTEEVE QAIKEAQHGN

NQPAVKE
Length:557
Mass (Da):62,388
Last modified:March 21, 2006 - v1
Checksum:iBB3D044040212E82
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000255 Genomic DNA. Translation: ABD21577.1.
RefSeqiYP_493890.1. NC_007793.1.

Genome annotation databases

EnsemblBacteriaiABD21577; ABD21577; SAUSA300_1193.
GeneIDi3914295.
KEGGisaa:SAUSA300_1193.
PATRICi19591755. VBIStaAur129981_1305.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000255 Genomic DNA. Translation: ABD21577.1 .
RefSeqi YP_493890.1. NC_007793.1.

3D structure databases

ProteinModelPortali Q2FHD8.
SMRi Q2FHD8. Positions 3-546.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 451515.SAUSA300_1193.

Proteomic databases

PRIDEi Q2FHD8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD21577 ; ABD21577 ; SAUSA300_1193 .
GeneIDi 3914295.
KEGGi saa:SAUSA300_1193.
PATRICi 19591755. VBIStaAur129981_1305.

Phylogenomic databases

eggNOGi COG0578.
HOGENOMi HOG000004812.
KOi K00111.
OMAi NDIEASW.
OrthoDBi EOG651SR7.

Enzyme and pathway databases

UniPathwayi UPA00618 ; UER00674 .
BioCyci SAUR451515:GH3C-1193-MONOMER.

Family and domain databases

InterProi IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view ]
Pfami PF01266. DAO. 1 hit.
[Graphical view ]
PRINTSi PR01001. FADG3PDH.
PROSITEi PS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus."
    Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G., Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F., Perdreau-Remington F.
    Lancet 367:731-739(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USA300.

Entry informationi

Entry nameiGLPD_STAA3
AccessioniPrimary (citable) accession number: Q2FHD8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: March 21, 2006
Last modified: October 1, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3