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Q2FH65

- TRPF_STAA3

UniProt

Q2FH65 - TRPF_STAA3

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene
trpF, SAUSA300_1266
Organism
Staphylococcus aureus (strain USA300)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciSAUR451515:GH3C-1266-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:SAUSA300_1266
OrganismiStaphylococcus aureus (strain USA300)
Taxonomic identifieri367830 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001939: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 210210N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotationPRO_1000197122Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi451515.SAUSA300_1266.

Structurei

3D structure databases

ProteinModelPortaliQ2FH65.
SMRiQ2FH65. Positions 1-205.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiPDYAGFV.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2FH65-1 [UniParc]FASTAAdd to Basket

« Hide

MKLKFCGFTS IKDVTAASQL PIDAIGFIHY EKSKRHQTIT QIKKLASAVP    50
NHIDKVCVMV NPDLTTIEHV LSNTSINTIQ LHGTESIDFI QEIKKKYSSI 100
KITKALAADE NIIQNINKYK GFVDLFIIDT PSVSYGGTGQ TYDWTILKHI 150
KDIPYLIAGG INSENIQTVN QLKLSHQGYD LASGIEVNGR KDIEKMTAIV 200
NIVKGDRDNE 210
Length:210
Mass (Da):23,389
Last modified:March 21, 2006 - v1
Checksum:iB178BE630DF7CF24
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000255 Genomic DNA. Translation: ABD22806.1.
RefSeqiYP_493963.1. NC_007793.1.

Genome annotation databases

EnsemblBacteriaiABD22806; ABD22806; SAUSA300_1266.
GeneIDi3913452.
KEGGisaa:SAUSA300_1266.
PATRICi19591917. VBIStaAur129981_1387.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000255 Genomic DNA. Translation: ABD22806.1 .
RefSeqi YP_493963.1. NC_007793.1.

3D structure databases

ProteinModelPortali Q2FH65.
SMRi Q2FH65. Positions 1-205.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 451515.SAUSA300_1266.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD22806 ; ABD22806 ; SAUSA300_1266 .
GeneIDi 3913452.
KEGGi saa:SAUSA300_1266.
PATRICi 19591917. VBIStaAur129981_1387.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi PDYAGFV.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci SAUR451515:GH3C-1266-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus."
    Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G., Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F., Perdreau-Remington F.
    Lancet 367:731-739(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USA300.

Entry informationi

Entry nameiTRPF_STAA3
AccessioniPrimary (citable) accession number: Q2FH65
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 21, 2006
Last modified: May 14, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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