Q2FH12 (Q2FH12_STAA3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL ABD22190.1
EC=1.5.1.3 EMBL ABD22190.1

Gene names

Name:	folA EMBL ABD22190.1
Ordered Locus Names:	SAUSA300_1319

Organism

Staphylococcus aureus (strain USA300) [Complete proteome] [HAMAP]

Taxonomic identifier

367830 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	159 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ABD22190.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2FH12 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: 811898409FEAFAAB	FASTA	159	18,251
	10 20 30 40 50 60 MTLSILVAHD LQRVIGFENQ LPWHLPNDLK HVKKLSTGHT LVMGRKTFES IGKPLPNRRN 70 80 90 100 110 120 VVLTSDTSFN VEGVDVIHSI EDIYQLPGHV FIFGGQTLFE EMIDKVDDMY ITVIEGKFRG 130 140 150 DTFFPPYTFE DWEVASSVEG KLDEKNTIPH TFLHLIRKK

References

[1]

"Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus." Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G., Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F., Perdreau-Remington F. Lancet 367:731-739(2006) [PubMed: 16517273] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000255 Genomic DNA. Translation: ABD22190.1.
RefSeq	YP_494016.1. NC_007793.1.
3D structure databases
ProteinModelPortal	Q2FH12.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000036721; EBSTAP00000035429; EBSTAG00000036719.
GeneID	3914467.
GenomeReviews	Gene locus SAUSA300_1319 in contig CP000255_GR.
KEGG	saa:SAUSA300_1319.
PATRIC	19592031. VBIStaAur129981_1444.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0262.
GeneTree	EBGT00050000024106.
HOGENOM	HBG665708.
OMA	QDEEGVI.
ProtClustDB	CLSK885344.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2FH12_STAA3

Accession

Primary (citable) accession number: Q2FH12

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)