ID   LACB_STAA3              Reviewed;         171 AA.
AC   Q2FET8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 18.
DE   RecName: Full=Galactose-6-phosphate isomerase subunit lacB;
DE            EC=5.3.1.26;
GN   Name=lacB; OrderedLocusNames=SAUSA300_2154;
OS   Staphylococcus aureus (strain USA300).
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=367830;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16517273; DOI=10.1016/S0140-6736(06)68231-7;
RA   Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA   Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA   Perdreau-Remington F.;
RT   "Complete genome sequence of USA300, an epidemic clone of community-
RT   acquired meticillin-resistant Staphylococcus aureus.";
RL   Lancet 367:731-739(2006).
CC   -!- CATALYTIC ACTIVITY: D-galactose 6-phosphate = D-tagatose 6-
CC       phosphate.
CC   -!- PATHWAY: Carbohydrate metabolism; galactose degradation; D-
CC       tagatose 6-phosphate from D-galactose 6-phosphate: step 1/1.
CC   -!- SUBUNIT: Heteromultimeric protein consisting of lacA and lacB (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the lacAB/rpiB family.
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DR   EMBL; CP000255; ABD22213.1; -; Genomic_DNA.
DR   RefSeq; YP_494790.1; -.
DR   GeneID; 3915291; -.
DR   GenomeReviews; CP000255_GR; SAUSA300_2154.
DR   KEGG; saa:SAUSA300_2154; -.
DR   HOGENOM; Q2FET8; -.
DR   OMA; Q2FET8; ETHHANQ.
DR   GO; GO:0050044; F:galactose-6-phosphate isomerase activity; IEA:HAMAP.
DR   GO; GO:0019512; P:lactose catabolic process via tagatose-6-ph...; IEA:HAMAP.
DR   HAMAP; MF_01556; -; 1.
DR   InterPro; IPR004784; LacB.
DR   InterPro; IPR003500; Rib/Gal_isomrase.
DR   Gene3D; G3DSA:3.40.1400.10; Rib/Gal_isomrase; 1.
DR   Pfam; PF02502; LacAB_rpiB; 1.
DR   PIRSF; PIRSF005384; RpiB_LacA_B; 1.
DR   TIGRFAMs; TIGR01119; lacB; 1.
DR   TIGRFAMs; TIGR00689; rpiB_lacA_lacB; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Isomerase; Lactose metabolism.
FT   CHAIN         1    171       Galactose-6-phosphate isomerase subunit
FT                                lacB.
FT                                /FTId=PRO_1000068926.
SQ   SEQUENCE   171 AA;  18951 MW;  10617F0F28536A13 CRC64;
     MKIALGCDHI VTDTKMRVSE FLKSKGHEVI DVGTYDFTRT HYPIFGKKVG EQVVSGNADL
     GVCICGTGVG INNAVNKVPG VRSALVRDMT SALYAKEELN ANVIGFGGRI IGELLMCDII
     DAFINAEYKP TEENKKLIAK IKHLETSNAD QADPHFFDEF LEKWDRGEYH D
//