Q2FDW1 (Q2FDW1_STAA3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hydroxymethylglutaryl-CoA reductase EMBL ABD22202.1
EC=1.1.1.88 EMBL ABD22202.1

Gene names

Ordered Locus Names:

SAUSA300_2483

Organism

Staphylococcus aureus (strain USA300) [Complete proteome] [HAMAP]

Taxonomic identifier

367830 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	425 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the HMG-CoA reductase family. RuleBase RU004268

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004269 EMBL ABD22202.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase (NADPH) activity Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2FDW1 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: 93338FC55C2DD044	FASTA	425	46,237
	10 20 30 40 50 60 MQNLDKNFRH LSRKEKLQQL VDKQWLSEEQ FDILLNHPLI DEEVANSLIE NVIAQGALPV 70 80 90 100 110 120 GLLPNIIVDD KAYVVPMMVE EPSVVAAASY GAKLVNQTGG FKTVSSERIM IGQIVFDGVD 130 140 150 160 170 180 DTEKLSADIK ALEKQIHKIA DEAYPSIKAR GGGYQRIAID TFPEQQLLSL KVFVDTKDAM 190 200 210 220 230 240 GANMLNTILE AITAFLKNEF PQSDILMSIL SNHATASVVK VQGEIDVKDL ARGERTGEEV 250 260 270 280 290 300 AKRMERASVL AQVDIHRAAT HNKGVMNGIH AVVLATGNDT RGAEASAHAY ASRDGQYRGI 310 320 330 340 350 360 ATWRYDQDRQ RLIGTIEVPM TLAIVGGGTK VLPIAKASLE LLNVESAQEL GHVVAAVGLA 370 380 390 400 410 420 QNFAACRALV SEGIQQGHMS LQYKSLAIVV GAKGDEIAKV AEALKKEPRA NTQAAEHILQ EIRQQ

References

[1]

"Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus." Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G., Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F., Perdreau-Remington F. Lancet 367:731-739(2006) [PubMed: 16517273] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000255 Genomic DNA. Translation: ABD22202.1.
RefSeq	YP_495117.1. NC_007793.1.
3D structure databases
ProteinModelPortal	Q2FDW1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000036521; EBSTAP00000035229; EBSTAG00000036519.
GeneID	3915280.
GenomeReviews	Gene locus SAUSA300_2483 in contig CP000255_GR.
KEGG	saa:SAUSA300_2483.
PATRIC	19594565. VBIStaAur129981_2658.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1257.
GeneTree	EBGT00050000024128.
HOGENOM	HBG477902.
OMA	NNKGIMN.
ProtClustDB	CLSK886059.
Family and domain databases
InterPro	IPR002202. HMG_CoA_Rdtase. IPR004553. HMG_CoA_Rdtase_bac-typ. IPR023074. HMG_CoA_Rdtase_cat. IPR023076. HMG_CoA_Rdtase_CS. IPR009023. HMG_CoA_Rdtase_NAD(P)-bd. IPR009029. HMG_CoA_Rdtase_sub-bd. [Graphical view]
Gene3D	G3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit. G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KO	K00054.
Pfam	PF00368. HMG-CoA_red. 1 hit. [Graphical view]
PRINTS	PR00071. HMGCOARDTASE.
SUPFAM	SSF55035. HMG_CoA_NAD_bind. 1 hit. SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMs	TIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITE	PS00066. HMG_COA_REDUCTASE_1. 1 hit. PS01192. HMG_COA_REDUCTASE_3. 1 hit. PS50065. HMG_COA_REDUCTASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2FDW1_STAA3

Accession

Primary (citable) accession number: Q2FDW1

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)