Q2EN89 (Q2EN89_PIG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
C-C motif chemokine 5 Ensembl ENSSSCP00000028561 Ensembl ENSSSCP00000018760

Submitted name:
CCL5 EMBL ABD18445.1

Gene names

Name:

CCL5 Ensembl ENSSSCP00000028561 Ensembl ENSSSCP00000018760

Organism

Sus scrofa (Pig) [Reference proteome]

Taxonomic identifier

9823 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Suina › Suidae › Sus

Protein attributes

Sequence length	91 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Cytokine SAAS SAAS000827
PTM	Disulfide bond SAAS SAAS000827
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	MAPK cascade Inferred from electronic annotation. Source: Compara activation of phospholipase D activity Inferred from electronic annotation. Source: Compara calcium ion transport Inferred from electronic annotation. Source: Compara cell-cell signaling Inferred from electronic annotation. Source: Compara cellular calcium ion homeostasis Inferred from electronic annotation. Source: Compara cellular protein complex assembly Inferred from electronic annotation. Source: Compara cellular response to fibroblast growth factor stimulus Inferred from electronic annotation. Source: Compara cellular response to interferon-gamma Inferred from electronic annotation. Source: Compara cellular response to interleukin-1 Inferred from electronic annotation. Source: Compara cellular response to organic cyclic compound Inferred from electronic annotation. Source: Compara cellular response to tumor necrosis factor Inferred from electronic annotation. Source: Compara eosinophil chemotaxis Inferred from electronic annotation. Source: Compara exocytosis Inferred from electronic annotation. Source: Compara inflammatory response Inferred from electronic annotation. Source: Compara leukocyte cell-cell adhesion Inferred from electronic annotation. Source: Compara lipopolysaccharide-mediated signaling pathway Inferred from electronic annotation. Source: Compara negative regulation by host of viral transcription Inferred from electronic annotation. Source: Compara negative regulation of G-protein coupled receptor protein signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of T cell apoptotic process Inferred from electronic annotation. Source: Compara negative regulation of chemokine-mediated signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of macrophage apoptotic process Inferred from electronic annotation. Source: Compara negative regulation of viral genome replication Inferred from electronic annotation. Source: Compara neutrophil activation Inferred from electronic annotation. Source: Compara positive regulation of T cell apoptotic process Inferred from electronic annotation. Source: Compara positive regulation of T cell chemotaxis Inferred from electronic annotation. Source: Compara positive regulation of T cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of calcium ion transport Inferred from electronic annotation. Source: Compara positive regulation of cell-cell adhesion mediated by integrin Inferred from electronic annotation. Source: Compara positive regulation of cellular biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of homotypic cell-cell adhesion Inferred from electronic annotation. Source: Compara positive regulation of macrophage chemotaxis Inferred from electronic annotation. Source: Compara positive regulation of monocyte chemotaxis Inferred from electronic annotation. Source: Compara positive regulation of natural killer cell chemotaxis Inferred from electronic annotation. Source: Compara positive regulation of phosphatidylinositol 3-kinase cascade Inferred from electronic annotation. Source: Compara positive regulation of smooth muscle cell migration Inferred from electronic annotation. Source: Compara positive regulation of smooth muscle cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of tyrosine phosphorylation of STAT protein Inferred from electronic annotation. Source: Compara protein kinase B signaling cascade Inferred from electronic annotation. Source: Compara protein tetramerization Inferred from electronic annotation. Source: Compara response to toxin Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara extracellular space Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	chemoattractant activity Inferred from electronic annotation. Source: Compara phosphatidylinositol phospholipase C activity Inferred from electronic annotation. Source: Compara phospholipase activator activity Inferred from electronic annotation. Source: Compara protein kinase activity Inferred from electronic annotation. Source: Compara receptor signaling protein tyrosine kinase activator activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2EN89 [UniParc]. Last modified March 21, 2006. Version 1. Checksum: 82EA6FC0D11EDE3C	FASTA	91	10,041
	10 20 30 40 50 60 MKVSTAALAV ILAMAALCAP ASASPYASDT TPCCFSYLSR PLPRAHLQEY FYTSSKCSMA 70 80 90 AVVFITRKNR QVCANPEKKW VREYINSLEL S

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular Cloning of Porcine Chemokine, CCL5." Yang J., Cho B.R., Choi I., Kim D., Kim S.D., Kim J.Y., Ahn C. Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Porcine genome sequencing project Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION.
[4]	Ensembl Submitted (NOV-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU896616 Genomic DNA. No translation available. DQ372066 mRNA. Translation: ABD18445.1.
RefSeq	NP_001123418.1. NM_001129946.1.
UniGene	Ssc.22030.
3D structure databases
SMR	Q2EN89. Positions 24-91.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSSSCT00000019271; ENSSSCP00000018760; ENSSSCG00000017705. ENSSSCT00000033821; ENSSSCP00000028561; ENSSSCG00000017705.
GeneID	396613.
KEGG	ssc:396613.
Organism-specific databases
CTD	6352.
Phylogenomic databases
GeneTree	ENSGT00560000077010.
HOGENOM	HOG000036685.
HOVERGEN	HBG017871.
KO	K12499.
OMA	QEYFYTS.
Gene expression databases
ArrayExpress	Q2EN89.
Family and domain databases
InterPro	IPR000827. Chemokine_CC_CS. IPR001811. Chemokine_IL8-like_dom. [Graphical view]
Pfam	PF00048. IL8. 1 hit. [Graphical view]
SMART	SM00199. SCY. 1 hit. [Graphical view]
SUPFAM	SSF54117. Chemokine_IL8. 1 hit.
PROSITE	PS00472. SMALL_CYTOKINES_CC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2EN89_PIG

Accession

Primary (citable) accession number: Q2EN89

Entry history

Integrated into UniProtKB/TrEMBL:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	May 1, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)