Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Serine/threonine-protein phosphatase

Gene

PPP1CC

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphataseSAAS annotation
LigandManganeseSAAS annotation, Metal-bindingSAAS annotation

Enzyme and pathway databases

ReactomeiR-SSC-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-SSC-2467813 Separation of Sister Chromatids
R-SSC-2500257 Resolution of Sister Chromatid Cohesion
R-SSC-5663220 RHO GTPases Activate Formins
R-SSC-68877 Mitotic Prometaphase

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
Name:PPP1CCImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 14

Subcellular locationi

Expressioni

Gene expression databases

GenevisibleiQ2EHH7 SS

Structurei

3D structure databases

ProteinModelPortaliQ2EHH7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini121 – 126SER_THR_PHOSPHATASEInterPro annotation6

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0374 Eukaryota
COG0639 LUCA
GeneTreeiENSGT00530000062911
HOGENOMiHOG000172697
HOVERGENiHBG000216
KOiK06269

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR037981 PPP1CC
IPR006186 Ser/Thr-sp_prot-phosphatase
IPR031675 STPPase_N
PANTHERiPTHR11668:SF204 PTHR11668:SF204, 1 hit
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PF16891 STPPase_N, 1 hit
PRINTSiPR00114 STPHPHTASE
SMARTiView protein in SMART
SM00156 PP2Ac, 1 hit
PROSITEiView protein in PROSITE
PS00125 SER_THR_PHOSPHATASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q2EHH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADIDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP
60 70 80 90 100
ILLELEAPLK ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS
110 120 130 140 150
LETICLLLAY KIKYPENFFL LRGNHECASI NRIYGFYDEC KRRYNIKLWK
160 170 180 190 200
TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL QSMEQIRRIM RPTDVPDQGL
210 220 230 240 250
LCDLLWSDPD KDVLGWGEND RGVSFTFGAE VVAKFLHKHD LDLICRAHQV
260 270 280 290 300
VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAE
310 320
KKKPNATRPV TPPRGMITKQ AKK
Length:323
Mass (Da):36,984
Last modified:March 21, 2006 - v1
Checksum:i4E28412C16898615
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000096 Genomic DNA No translation available.
DQ380141 mRNA Translation: ABD38709.1
RefSeqiNP_001038025.1, NM_001044560.1
UniGeneiSsc.11661

Genome annotation databases

EnsembliENSSSCT00000057780; ENSSSCP00000040461; ENSSSCG00000009828
GeneIDi733612
KEGGissc:733612

Similar proteinsi

Entry informationi

Entry nameiQ2EHH7_PIG
AccessioniPrimary (citable) accession number: Q2EHH7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health