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Q2A1C2

- Q2A1C2_FRATH

UniProt

Q2A1C2 - Q2A1C2_FRATH

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Protein

Glutamate decarboxylase

Gene

FTL_1863

Organism
Francisella tularensis subsp. holarctica (strain LVS)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciFTUL376619:GI22-1913-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:FTL_1863Imported
OrganismiFrancisella tularensis subsp. holarctica (strain LVS)Imported
Taxonomic identifieri376619 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
ProteomesiUP000001944: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi119857.FTL_1863.

Structurei

3D structure databases

ProteinModelPortaliQ2A1C2.
SMRiQ2A1C2. Positions 13-370.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiNCQENTR.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2A1C2 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALHGKKDTI DNLDFFEQSL PKFKLPLNSQ DPLEVYQEIK DELMLDGNSK
60 70 80 90 100
QNLETFCQTE VDDFIHKLMD DCIDKNMIDK DEYPQTAEIE SRCVNILANL
110 120 130 140 150
WNSSAENAIG CSTTGSSEAA MLGGMAMKWR WRDKMKAQGK DYTKPNLVTG
160 170 180 190 200
PVQVCWHKFA RYWDIELREI PMSNESLIMT PEAVLERCDE NTIGVVPTLG
210 220 230 240 250
VTFTGQYEPV EQVCKALDDF ERQTGVDIPV HVDAASGGFL APFVEPELKW
260 270 280 290 300
DFRLPISPLG VGWVIWADKK YLPDDLIFNV NYLGGNMPTF ALNFSRPGGQ
310 320 330 340 350
IVAQYYNFVR LGFEGYKKVH QLCYDIAEYI AKELRKMEIF EIIHAGEGGI
360 370
PAVSWSLKAT KEYSLFDISE SSR
Length:373
Mass (Da):42,362
Last modified:April 4, 2006 - v1
Checksum:i0911AA3E533856C8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM233362 Genomic DNA. Translation: CAJ80302.1.
RefSeqiYP_514480.1. NC_007880.1.

Genome annotation databases

EnsemblBacteriaiCAJ80302; CAJ80302; FTL_1863.
GeneIDi3950910.
KEGGiftl:FTL_1863.
PATRICi17944980. VBIFraTul90181_2021.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM233362 Genomic DNA. Translation: CAJ80302.1 .
RefSeqi YP_514480.1. NC_007880.1.

3D structure databases

ProteinModelPortali Q2A1C2.
SMRi Q2A1C2. Positions 13-370.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 119857.FTL_1863.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ80302 ; CAJ80302 ; FTL_1863 .
GeneIDi 3950910.
KEGGi ftl:FTL_1863.
PATRICi 17944980. VBIFraTul90181_2021.

Phylogenomic databases

HOGENOMi HOG000070228.
KOi K01580.
OMAi NCQENTR.
OrthoDBi EOG6TFCPW.

Enzyme and pathway databases

BioCyci FTUL376619:GI22-1913-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Francisella tularensis LVS (Live Vaccine Strain)."
    Chain P., Larimer F., Land M., Stilwagen S., Larsson P., Bearden S., Chu M., Oyston P., Forsman M., Andersson S., Lindler L., Titball R., Garcia E.
    Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LVSImported.

Entry informationi

Entry nameiQ2A1C2_FRATH
AccessioniPrimary (citable) accession number: Q2A1C2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: April 4, 2006
Last modified: October 1, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3