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Protein

Phospholipid phosphatase-related protein type 2

Gene

PLPPR2

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Phospholipid phosphatase-related protein type 2By similarity (EC:3.1.3.4)
Alternative name(s):
Lipid phosphate phosphatase-related protein type 21 Publication
Plasticity-related gene 4 proteinBy similarity
Short name:
PRG-4By similarity
Gene namesi
Name:PLPPR2By similarity
Synonyms:LPPR21 Publication, PRG4By similarity
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei14 – 3421HelicalSequence analysisAdd
BLAST
Transmembranei66 – 8621HelicalSequence analysisAdd
BLAST
Transmembranei147 – 16721HelicalSequence analysisAdd
BLAST
Transmembranei176 – 19621HelicalSequence analysisAdd
BLAST
Transmembranei203 – 22321HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 389389Phospholipid phosphatase-related protein type 2PRO_0000317537Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi102 – 1021N-linked (GlcNAc...)Sequence analysis
Modified residuei236 – 2361PhosphoserineBy similarity
Modified residuei249 – 2491PhosphoserineBy similarity

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiQ29RT8.
PRIDEiQ29RT8.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000043142.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi337 – 3459Poly-Gly

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3030. Eukaryota.
COG0671. LUCA.
HOGENOMiHOG000286008.
HOVERGENiHBG108093.
InParanoidiQ29RT8.
KOiK19581.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR028679. LPPR2.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PANTHERiPTHR10165:SF15. PTHR10165:SF15. 1 hit.
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 2 hits.

Sequencei

Sequence statusi: Complete.

Q29RT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGGRPQLKR SFSIIPCFVF VEILLGELAR AFFPAPPSAV PIIGESTIVS
60 70 80 90 100
GACCRFSPPL RRLVRFLGVY SFGLFTTTIF ANAGQVVTGN PTPHFLSVCR
110 120 130 140 150
PNYTALGCPP PSPDRPGPDR FVNDQGACAG SPSLVAAARR AFPCKDAALC
160 170 180 190 200
AYAVTYTAMY VTLVFRVKGS RLVKPSLCLA LLCPAFLVGV VRVAEYRNHW
210 220 230 240 250
SDVLAGFLTG AAIATFLVTC VVHNFQSRPP SGRRLSPWED LSQAPTMDSP
260 270 280 290 300
LEKLSVAQEP EGCRSHSTPA RLTPSKPQNC ARRGHLIPNC VSSRAPAMCS
310 320 330 340 350
SPRVPRPRLR SEPTPLPLPL PLPAPAPSQG PSPSSPGPGG PGGGGSRGRK
360 370 380
LLLPTPLLRD LYTLSGLYPS PFHRDNFSPY LFASRDHLL
Length:389
Mass (Da):41,632
Last modified:April 4, 2006 - v1
Checksum:i9A5166C408797A44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC114023 mRNA. Translation: AAI14024.1.
RefSeqiNP_001039713.1. NM_001046248.2.
UniGeneiBt.10704.

Genome annotation databases

GeneIDi520247.
KEGGibta:520247.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC114023 mRNA. Translation: AAI14024.1.
RefSeqiNP_001039713.1. NM_001046248.2.
UniGeneiBt.10704.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000043142.

Proteomic databases

PaxDbiQ29RT8.
PRIDEiQ29RT8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi520247.
KEGGibta:520247.

Organism-specific databases

CTDi64748.

Phylogenomic databases

eggNOGiKOG3030. Eukaryota.
COG0671. LUCA.
HOGENOMiHOG000286008.
HOVERGENiHBG108093.
InParanoidiQ29RT8.
KOiK19581.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR028679. LPPR2.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PANTHERiPTHR10165:SF15. PTHR10165:SF15. 1 hit.
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Testis.

Entry informationi

Entry nameiPLPR2_BOVIN
AccessioniPrimary (citable) accession number: Q29RT8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: April 4, 2006
Last modified: June 8, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.