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Protein

Peptidyl-prolyl cis-trans isomerase

Gene

Dpse\GA17809

Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.UniRule annotation

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, RotamasePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomeraseUniRule annotation (EC:5.2.1.8UniRule annotation)
Short name:
PPIaseUniRule annotation
Gene namesi
Name:Dpse\GA17809Imported
ORF Names:Dpse_GA17809Imported, GA17809Imported
OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)Imported
Taxonomic identifieri46245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000001819 Componenti: Partially assembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0077818 Dpse\GA17809

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei204 – 229HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0077818

Interactioni

Protein-protein interaction databases

STRINGi7237.FBpp0285180

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 189PPIase cyclophilin-typeInterPro annotationAdd BLAST161

Sequence similaritiesi

Belongs to the cyclophilin-type PPIase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

InParanoidiQ29NN3
KOiK01802
OMAiRIILCSA

Family and domain databases

Gene3Di2.40.100.10, 1 hit
InterProiView protein in InterPro
IPR029000 Cyclophilin-like_dom_sf
IPR024936 Cyclophilin-type_PPIase
IPR020892 Cyclophilin-type_PPIase_CS
IPR002130 Cyclophilin-type_PPIase_dom
PANTHERiPTHR11071 PTHR11071, 1 hit
PfamiView protein in Pfam
PF00160 Pro_isomerase, 1 hit
PRINTSiPR00153 CSAPPISMRASE
SUPFAMiSSF50891 SSF50891, 1 hit
PROSITEiView protein in PROSITE
PS00170 CSA_PPIASE_1, 1 hit
PS50072 CSA_PPIASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q29NN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFIHVALYC YGLLATVSGL SFTVTSRIFM DVKHNKQPIG RITFGLFGKL
60 70 80 90 100
APKTVANFRH ICLRGINGTS YVGARFHRVV DRFLVQGGDI LHGDGTGSIS
110 120 130 140 150
IYGDYFEDED KALAVEHNRP GYLGMANRGP DTNGCQFYVT TVGAKWLDGK
160 170 180 190 200
HTVFGKVLEG MDTIYAIEDV KTDTDDFPVQ PVVISNCGEI PTEQFEFYPD
210 220 230
DYNILGWIKA AGLPVTSSFL VLLIFHYFFR QLNMYC
Length:236
Mass (Da):26,406
Last modified:October 14, 2008 - v2
Checksum:iAC5181ABFC007681
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH379059 Genomic DNA Translation: EAL34185.2
RefSeqiXP_001357119.2, XM_001357083.3

Genome annotation databases

EnsemblMetazoaiFBtr0286742; FBpp0285180; FBgn0077818
GeneIDi4817777
KEGGidpo:Dpse_GA17809

Similar proteinsi

Entry informationi

Entry nameiQ29NN3_DROPS
AccessioniPrimary (citable) accession number: Q29NN3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: October 14, 2008
Last modified: March 28, 2018
This is version 88 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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