Q29MC7 (Q29MC7_DROPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GA17300 EMBL EAL33767.2
EC=6.1.1.4 EMBL EAL33767.2

Gene names

Name:	GA17300 FlyBase FBgn0077313
Synonyms:	Dpse\GA17300 EMBL EAL33767.2
ORF Names:	Dpse_GA17300 EMBL EAL33767.2

Organism

Drosophila pseudoobscura pseudoobscura (Fruit fly) [Reference proteome] EMBL EAL33767.2

Taxonomic identifier

46245 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › obscura group › pseudoobscura subgroup › Drosophila pseudoobscura

Protein attributes

Sequence length	1180 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. RuleBase RU003489

Ontologies

Keywords
Biological process	Protein biosynthesis RuleBase RU003489
Ligand	ATP-binding RuleBase RU003489 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase RuleBase RU003489 Ligase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	leucyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro regulation of translational fidelity Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW aminoacyl-tRNA editing activity Inferred from electronic annotation. Source: InterPro leucine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q29MC7 [UniParc]. Last modified October 14, 2008. Version 2. Checksum: 38D06C627E06CE7B	FASTA	1,180	134,825
	10 20 30 40 50 60 MANIERKGTF KVEYLQKIER EVQERWEKEQ VHQTDAPAAP KKEQSEKFFV TFPFPYMNGR 70 80 90 100 110 120 LHLGHTFSLS KAEFAVRYHR LKGRRVLWPF GFHCTGMPIK ACADKLTREM ELFGYPPQFP 130 140 150 160 170 180 EAVEEAPVEE TKSEIPKDKS KGKKSKAVAK TGAAKYQWQI MQSLGLKDEE IKEFSDPQHW 190 200 210 220 230 240 LNYFPPLAIQ DLKSIGAHID WRRKFITTDA NPFFDSFVRW QFNHLKQRGK IMYGKRYTIY 250 260 270 280 290 300 SPKDGQPCMD HDRSTGEGVG PQEYTLIKMK VLQAPKVLSA IKKPIYMVAA TLRPETMYGQ 310 320 330 340 350 360 TNCWLHPDIK YIAWQTSRDE VWISTRRAAR NMAYQGFTAE EGNIVVLAEI TGLELLGTPL 370 380 390 400 410 420 SAPLTSHKII YTLPMLSIKA DKGTGVVTSV PSDSPDDYAA LVDLQKKEAF RQKYGLKDEM 430 440 450 460 470 480 VLNYEPFPII EVPTLGKLCA VHAYNTLKIQ SQNDKDKLAE AKEMCYLKSF YDGIMLVGEF 490 500 510 520 530 540 AGSKVQDVKK NLQKKMVDAN EAEVYYEPEK TILSRSADEC VVALCNQWYV TYGETVWKEQ 550 560 570 580 590 600 AFKILHDMET FHEEARNNFE ACLNWLHEYA CSRTYGLGTK LPWDEQWLIE SLSDSTIYMA 610 620 630 640 650 660 YYTVVHLIQG GSLRGENPGP FGITPADMTS EVWDYIFFKE TPPPKKSNIK LEHLAVLRRE 670 680 690 700 710 720 FEYWYPMDLR VSGKDLINNH LTFTLYNHAA IWPKDDTKWP KGMRVNGHLL LNSAKMSKSD 730 740 750 760 770 780 GNFLTLTDAV EKFSADGMRL CLADAGDSIE DANFVVSTAD AGILRLFTFI EWVKEMLETK 790 800 810 820 830 840 STLRKGAART FNDQVFLSEL NLKTQQTDDN YRKMLFKEAL RSGFYELQLA RDKYRELCGT 850 860 870 880 890 900 QGMHVELVLE FIRRQALLVA PICPHMAEHV WGLLGNKESI VHARWPEVGA INELDIMSSE 910 920 930 940 950 960 YLMESAHAFR LNLKNLLQLK AKGGKEKALD PQTAKPNRAL IWAAKTYPPW QCCVLDTMRE 970 980 990 1000 1010 1020 LFNMSKALPD NKVIAATLQQ KAELKKFMKR VMPFAQMIRE KVESGKGVAA LAVNLDFDER 1030 1040 1050 1060 1070 1080 QVLISNLEYL KNTLDLDSLE VKYTDDPSAP EKTREEVRPG SPFISFSVAP NVSVELVNPT 1090 1100 1110 1120 1130 1140 ERSSLFQINT IISEGDTVQS LREKISKVIG LKTDLSNLKI WRFDDLLLGP RKIPNFQDYK 1150 1160 1170 1180 TGKTLLSEGN FILDVAAKRV SVEQGGKLTE VGRNLIYVVE

References

[1]

"Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution." Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L. , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A. Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MV2-25 / Tucson 14011-0121.94.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH379060 Genomic DNA. Translation: EAL33767.2.
RefSeq	XP_001356702.2. XM_001356666.2.
3D structure databases
ProteinModelPortal	Q29MC7.
ModBase	Search...
Protein-protein interaction databases
STRING	7237.FBpp0280597.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0282159; FBpp0280597; FBgn0077313.
GeneID	4816912.
KEGG	dpo:Dpse_GA17300.
Organism-specific databases
FlyBase	FBgn0077313. Dpse\GA17300.
Phylogenomic databases
InParanoid	Q29MC7.
KO	K01869.
OMA	LRTFTIP.
OrthoDB	EOG4GTHTR.
Family and domain databases
Gene3D	3.40.50.620. 3 hits. 3.90.740.10. 1 hit.
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR002300. aa-tRNA-synth_Ia. IPR004493. Leu-tRNA-synth_Ia_arc/euk. IPR015413. Methionyl/Leucyl_tRNA_Synth. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. IPR013155. V/L/I-tRNA-synth_anticodon-bd. IPR009008. Val/Leu/Ile-tRNA-synth_edit. [Graphical view]
Pfam	PF08264. Anticodon_1. 1 hit. PF00133. tRNA-synt_1. 2 hits. PF09334. tRNA-synt_1g. 1 hit. [Graphical view]
SUPFAM	SSF47323. tRNAsyn_1a_bind. 1 hit. SSF50677. ValRS_IleRS_edit. 1 hit.
TIGRFAMs	TIGR00395. leuS_arch. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q29MC7_DROPS

Accession

Primary (citable) accession number: Q29MC7

Entry history

Integrated into UniProtKB/TrEMBL:	April 4, 2006
Last sequence update:	October 14, 2008
Last modified:	April 3, 2013
This is version 53 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)