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Q29I35 (ARM_DROPS) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Armadillo segment polarity protein
Gene names
Name:arm
ORF Names:GA27602
OrganismDrosophila pseudoobscura pseudoobscura (Fruit fly) [Reference proteome]
Taxonomic identifier46245 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Protein attributes

Sequence length832 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May associate with CadN and participate in the transmission of developmental information. Can associate with alpha-catenin. Accumulates through wg signaling; arm function in wg signal transduction is required early in development for determination of neuroblast fate. Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis By similarity. UniProtKB P18824

Subcellular location

Cytoplasm By similarity. Cell membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Cell junctionadherens junction By similarity. Note: Inner surface of cell membrane and adherens junction By similarity. UniProtKB P18824

Sequence similarities

Belongs to the beta-catenin family.

Contains 10 ARM repeats.

Sequence caution

The sequence EDY72488.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 832832Armadillo segment polarity protein
PRO_0000312834

Regions

Repeat149 – 18840ARM 1
Repeat191 – 23141ARM 2
Repeat233 – 27240ARM 3
Repeat275 – 31440ARM 4
Repeat359 – 39739ARM 5
Repeat398 – 43740ARM 6
Repeat440 – 48142ARM 7
Repeat487 – 52741ARM 8
Repeat597 – 63640ARM 9
Repeat638 – 67740ARM 10

Sequences

Sequence LengthMass (Da)Tools
Q29I35 [UniParc].

Last modified January 20, 2009. Version 2.
Checksum: 52205E16C85BE598

FASTA83290,293
        10         20         30         40         50         60 
MSYMPAQNRT MSHNNQYNPP DLPPMVSAKE QTLMWQQNSY LGDSGIHSGA VTQVPSLSGK 

        70         80         90        100        110        120 
EDEEMEGDPL MFDLDTGFPQ NFTQDQVDDM NQQLSQTRSQ RVRAAMFPET LEEGIEIPST 

       130        140        150        160        170        180 
QFDPQQPTAV QRLSEPSQML KHAVVNLINY QDDAELATRA IPELIKLLND EDQVVVSQAA 

       190        200        210        220        230        240 
MMVHQLSKKE ASRHAIMNSP QMVAALVRAI SNSNDLESTK AAVGTLHNLS HHRQGLLAIF 

       250        260        270        280        290        300 
KSGGIPALVK LLSSPVESVL FYAITTLHNL LLHQDGSKMA VRLAGGLQKM VTLLQRNNVK 

       310        320        330        340        350        360 
FLAIVTDCLQ ILAYGNQESK LIILASGGPN ELVRIMRSYD YEKLLWTTSR VLKVLSVCSS 

       370        380        390        400        410        420 
NKPAIVDAGG MQALAMHLGN MSPRLVQNCL WTLRNLSDAA TKVEGLEALL QSLVQVLGST 

       430        440        450        460        470        480 
DVNVVTCAAG ILSNLTCNNQ RNKATVCQVG GVDALVRTII NAGDREEITE PAVCALRHLT 

       490        500        510        520        530        540 
SRHVDSELAQ NAVRLNYGLS VIVKLLHPPS RWPLIKAVIG LIRNLALCPA NHAPLREHGA 

       550        560        570        580        590        600 
IHHLVRLLMR AFQDTERQRS SIATTGSQQP SAYADGVRME EIVEGTVGAL HILARESHNR 

       610        620        630        640        650        660 
ALIRQQSVIP IFVRLLFNEI ENIQRVAAGV LCELAADKEG AEIIEQEGAT GPLTDLLHSR 

       670        680        690        700        710        720 
NEGVATYAAA VLFRMSEDKP QDYKKRLSIE LTNSLLREDN NIWANADLGM GPDLQVGSLQ 

       730        740        750        760        770        780 
GASALILLLY IFSISPYRLF AGYDTLPIDS MQGLEISSPV GGGGATGNSG GVNSASAGSG 

       790        800        810        820        830 
AVVPPSGAPT SPYSMDMDVG EIDAGALNFD LDAMPTPPND NNNLAAWYDT DC 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH379064 Genomic DNA. Translation: EDY72488.1. Sequence problems.
RefSeqXP_002133861.1. XM_002133825.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7237.FBpp0285007.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6901160.
KEGGdpo:Dpse_GA27602.

Organism-specific databases

FlyBaseFBgn0248967. Dpse\GA27602.

Phylogenomic databases

eggNOGNOG297695.
InParanoidQ29I35.
KOK02105.
OrthoDBEOG7X9G6B.

Family and domain databases

Gene3D1.25.10.10. 1 hit.
InterProIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR013284. Beta-catenin.
IPR002553. Clathrin/coatomer_adapt-like_N.
[Graphical view]
PfamPF01602. Adaptin_N. 1 hit.
PF00514. Arm. 3 hits.
[Graphical view]
PRINTSPR01869. BCATNINFAMLY.
SMARTSM00185. ARM. 12 hits.
[Graphical view]
SUPFAMSSF48371. SSF48371. 1 hit.
PROSITEPS50176. ARM_REPEAT. 9 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARM_DROPS
AccessionPrimary (citable) accession number: Q29I35
Secondary accession number(s): B5DLU2
Entry history
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: January 20, 2009
Last modified: February 19, 2014
This is version 48 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase