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Q29G04

- Q29G04_DROPS

UniProt

Q29G04 - Q29G04_DROPS

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Protein
Submitted name:

GA14357

Gene

Dpse\GA14357

Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. histone-lysine N-methyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
GA14357Imported (EC:2.1.1.43Imported)
Gene namesi
Name:Dpse\GA14357Imported
ORF Names:Dpse_GA14357Imported, GA14357Imported
OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)Imported
Taxonomic identifieri46245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000001819: Partially assembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0074385. Dpse\GA14357.

Subcellular locationi

GO - Cellular componenti

  1. chromosome Source: InterPro
  2. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7237.FBpp0272204.

Family & Domainsi

Sequence similaritiesi

Contains 1 post-SET domain.UniRule annotation
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Phylogenomic databases

InParanoidiQ29G04.
KOiK11423.
OrthoDBiEOG7DFXBB.

Family and domain databases

InterProiIPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR013257. SRI.
IPR001202. WW_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
PF08236. SRI. 1 hit.
[Graphical view]
SMARTiSM00384. AT_hook. 2 hits.
SM00570. AWS. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q29G04-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDEPNPMPST SVPTTPRGRG RGRPPKREQP AQPPDTDLQS LQDASGVGGS
60 70 80 90 100
VVRPCSPNTI RRSSRKRFCK FDVRDVLCLR KEHKIQIEGR IDSNVPDTAA
110 120 130 140 150
AAAAAAAATA ATAATAATAA VVAVAPPATA AAAATLPPSA NRLFSMFPST
160 170 180 190 200
RPPPKLPPPP PVLGIFVKPR STPSLIVAQL NSEPSSSCNP STASTATVTA
210 220 230 240 250
ASASAPAARG GRGRPRAKNK LEKTISQSQS LSFSDSDSTG ASSGSTGSRG
260 270 280 290 300
GSTDSNETTA SRRKCRVTLK RLNFVQRQGS WDSGDSSTVL GDTVVDVSSS
310 320 330 340 350
SSSAPSSPVM QDDNAFDEQP KREPMTMSVS MPTADDDDDD SSDSQIIFTE
360 370 380 390 400
IDTGKEVPAR MKEENQEEPK LKLELKVEPQ IETEIEQQEE QEPEQEHDHE
410 420 430 440 450
VRNLMMEITN GSRNLWFFDD EEADEAETSP ASLMAMRRSK RTAKTEADCS
460 470 480 490 500
SSSSHVGKTL EETFAEIAAA SSEQIFLKAE SDEGEEEEHT LIDLIEESQE
510 520 530 540 550
EQGIQGEYEM VIEEEMKDEV QVKVIELDGL VFTATESESE ATAVEATLIS
560 570 580 590 600
EHQDDAVATE VTLKESPEKS PRTSTSGSTS ASTRVLPKEE PQAIILFEVE
610 620 630 640 650
AAKEDATTEQ SNVNVDVPPD PQEPDILEDV IVPNPIPIPI PMKAMPEPQP
660 670 680 690 700
EISLQIESSK TLPQWPLQEE KNKEKEVGLP EDTILIEIAM ESISKPTHAA
710 720 730 740 750
KSPAVEEPPA EEALKENEKV SPIKGPAKAD QSAGSPSSSS RHSFHASLNP
760 770 780 790 800
SPTATPIAIP IPEGTEASSA SGFVGCNVIF QALDIANALP LREDTHKKLK
810 820 830 840 850
LEAKKGSPPI PSTGEECLES TNNSHNPLND MKPLANGHNR GSDAIGRPSS
860 870 880 890 900
RNDDLKGEEE YSSSSEQAKQ SKEETPESSE GKKGSESATA KPKRRLTTTS
910 920 930 940 950
ELPHSAADEE GKHKSKRKFR CSAVASSPSA SPSDSRKDEA KRESPGASPK
960 970 980 990 1000
KGKPMPSRRF TTIDRPSSNA TSSGAASGEF SKYETRKPSP TASNASVKRR
1010 1020 1030 1040 1050
PTISEGSLSS SVESLVQKDS KKDEGKTESG ETLSPASKAS MKRRPTIGGR
1060 1070 1080 1090 1100
SSSASSSVES LTRKTASPGG TLSPANLTKN IRKSRSSGEW LERADSRKDK
1110 1120 1130 1140 1150
SGAVNRTSPR PQSPSPAPSP APSPAPSPAA SPAPVPMGPK QESQGRAMPL
1160 1170 1180 1190 1200
RRLTTIDRPS SSANPKGARP SFEQLLGQAD SYVNPQKKRC PTTSECSSPA
1210 1220 1230 1240 1250
SGESVARTIR SRRFTTIDRT SLNHGSPSDS RETQSKPSSP REQSPSDGDG
1260 1270 1280 1290 1300
SRGKLAKKID ISRLPLMEPR TNPSAAAVGS ITPELIEACF KDFASRADDA
1310 1320 1330 1340 1350
GAPAEKLPRT EGKLPLSQSP AAPKQDTEQK TPSHSHSQDT RDASRSISSS
1360 1370 1380 1390 1400
SSTSSSKPAS RTSSPAHEPK IKKINARRKI MQEPRIATPE LQSSNAKKGS
1410 1420 1430 1440 1450
PRTGSPELLL ENYSMNTEKN TDGMARGRND SPAQKAEKAE KVPIPKRGTP
1460 1470 1480 1490 1500
QSKQGSGLGS PMLLDQHHRM ITICAEPVPV PVLVPVPVLA AGVAAASPLR
1510 1520 1530 1540 1550
NADPRVRNAS PADPIPIPIP IPTATPMFMP IPRDRALPKK AVPSVTTPPS
1560 1570 1580 1590 1600
KQAVPTPKKP RAPKAGAKRA EESPEPSSSR KRRPTATTKA TDDVQAMQQV
1610 1620 1630 1640 1650
TTLALPLQQT QTEAMDSEST ESSVGKGKRW DVQPPASAAA TASTATPIEA
1660 1670 1680 1690 1700
LPASTYAAPP SAPAAEVEPP DTLKDIVKFI EDGVNLLKRN YKHDEDEDQP
1710 1720 1730 1740 1750
DEPPKLQQEM QDPMASVSSM ETPSVTRSPS PSLLPLPLPV GSASASPSAS
1760 1770 1780 1790 1800
VNSRANSTGE DSSPVQLQLL QGSNGDVSAG GVRRSHRIKQ KPQGPKASQG
1810 1820 1830 1840 1850
RGVASSAPPI SMEDQMAELA NTESQNEQFL RSEGLLTFQQ LRENYYRCAR
1860 1870 1880 1890 1900
QVSQENAEMQ CDCFLTGDEE AQGHLCCGAG CINRMLMIEC GPLCTNGDRC
1910 1920 1930 1940 1950
TNKRFQLHQC WPCRVFRTEK KGCGITAELQ IPAGEFIMEY VGEVIDSEEF
1960 1970 1980 1990 2000
ERRQHRYSKD RNRHYYFMAL RGEAIIDATM RGNISRYINH SCDPNAETQK
2010 2020 2030 2040 2050
WTVNGELRIG FFSLKNILPG EEITFDYQYQ RYGRDAQRCY CEAANCRGWI
2060 2070 2080 2090 2100
GTEPESDEGE QKNENNSEPA LATEDTDSGG EAESEAEGPE QSKSKGRAKT
2110 2120 2130 2140 2150
TSSSKFKVKL PAVGSKEQRK KRETAAKAKE REREFKAGRW LKPTPGGSSS
2160 2170 2180 2190 2200
AEKKAKPKVN KFHPMLEDPD VLEQLSLLSR SGLKNQLDTL RISRIMVRAK
2210 2220 2230 2240 2250
LLTTRIQLLQ VLTRGELPCR RLFLDYHGLR LLHAWISENG NEQQLRTALL
2260 2270 2280 2290 2300
DALEALPIPN RTMLNESRVY QSVQQWSAGL TGQQSQLRSP EQSALRKRMQ
2310 2320 2330 2340 2350
GLISKWSSLP EIFRIPKRER IEQMKEHERE ADRTGERPTE KHVASHHLTA
2360 2370 2380 2390 2400
ASALEDSARD SSTDRYRQDR FRRDTIGSRN SSQHQKPPMS RMSGNNTICT
2410 2420 2430 2440 2450
ITTQPKGSNP SEGQPRTEMR RRPDNSGPTV EPRRGGAPLS KELRRSLFER
2460 2470 2480 2490 2500
KVAQDEAEKR VCSEDWREHE LRCEYFGADI NTDPKMLPFS HNTETGEWFN
2510 2520 2530 2540 2550
SEDAPVMAPL RTDLALAPSP EISEQDMMPA EYKLPASVDP LPPSWHWSRT
2560 2570 2580 2590 2600
MDGDIFYYNL RDRIPQWLPP SPEQRLQTLL EEEPQQPLQE LDPALLAEEL
2610 2620 2630 2640 2650
ISVDPDYVGS LSSKSLAQHI ETKVRERREI RHKKLCSVRV ISPRRDEDRL
2660 2670 2680 2690 2700
YNQLESRKYK ENKEKIRRRK EIYRRQRASA DTVAVSSEAS TDAEAWSTPR
2710 2720 2730 2740 2750
YLYSSDEDTD TAHAPPLEGI IYGFNGSAGA LFATSKVDEL EAELDLEPST
2760 2770 2780 2790 2800
SAYALACLNK PQQIPTLVTG GNGGAIKRKL PPLPPHTPEK PAGALPERKS
2810 2820 2830 2840 2850
RSHDRRAPKR KMLLNSSKSG RDSVVKFRFE ISGHVADFLR PFRKDSCQMG
2860 2870 2880 2890 2900
RITSDAAYKF LIKRLTEHII TKEMRYCEMS GHPLICNDSV KHKSHEFINQ
2910
YMLKKGRVYV MPADEALL
Length:2,918
Mass (Da):318,926
Last modified:October 14, 2008 - v2
Checksum:i5BCA574C1F22D4F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH379065 Genomic DNA. Translation: EAL31425.2.
RefSeqiXP_001354372.2. XM_001354336.2.

Genome annotation databases

EnsemblMetazoaiFBtr0273766; FBpp0272204; FBgn0074385.
GeneIDi4814289.
KEGGidpo:Dpse_GA14357.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH379065 Genomic DNA. Translation: EAL31425.2 .
RefSeqi XP_001354372.2. XM_001354336.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7237.FBpp0272204.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0273766 ; FBpp0272204 ; FBgn0074385 .
GeneIDi 4814289.
KEGGi dpo:Dpse_GA14357.

Organism-specific databases

FlyBasei FBgn0074385. Dpse\GA14357.

Phylogenomic databases

InParanoidi Q29G04.
KOi K11423.
OrthoDBi EOG7DFXBB.

Family and domain databases

InterProi IPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR013257. SRI.
IPR001202. WW_dom.
[Graphical view ]
Pfami PF00856. SET. 1 hit.
PF08236. SRI. 1 hit.
[Graphical view ]
SMARTi SM00384. AT_hook. 2 hits.
SM00570. AWS. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00456. WW. 1 hit.
[Graphical view ]
SUPFAMi SSF51045. SSF51045. 1 hit.
PROSITEi PS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution."
    Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L.
    , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A.
    Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25 / Tucson 14011-0121.94Imported.
  2. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25Imported.

Entry informationi

Entry nameiQ29G04_DROPS
AccessioniPrimary (citable) accession number: Q29G04
Entry historyi
Integrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: October 14, 2008
Last modified: October 29, 2014
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3