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Protein
Submitted name:

GA11455

Gene

Dpse\GA11455

Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
GA11455Imported (EC:6.5.1.1Imported)
Gene namesi
Name:Dpse\GA11455Imported
ORF Names:Dpse_GA11455Imported, GA11455Imported
OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)Imported
Taxonomic identifieri46245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000001819: Partially assembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0071506. Dpse\GA11455.

Interactioni

Protein-protein interaction databases

STRINGi7237.FBpp0285479.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiQ29FM5.
KOiK10777.
OMAiISHFLCA.
OrthoDBiEOG7BKCT2.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q29FM5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDIATTVKFR DVCELFEKVK AAKKVQDKED VLRSYYESFC RHREAFRQAA
60 70 80 90 100
GLTDEQSENG SSSFHSVLRL LLPSADTRRD NYGLQITALG RLYTRVLQLT
110 120 130 140 150
RDSRDAIMLQ HRTGSSFRDY GDVVYAVLVS RCFNPPSDLR LNAIHEMLDT
160 170 180 190 200
IANEDTSVKE QELIRFTEQA SAREQKWLIR ILLKSLGLGI GEQRIFGVLH
210 220 230 240 250
PNAKDIYQRC SDLSHVCNLV ADKVSDLKVS DTKITGNSHP STVNLNAVIR
260 270 280 290 300
PFHQIRPMLC ERFPGDIQEL MQSDVLYLET KMDGERFQLH IDRGRFMYLS
310 320 330 340 350
RNGVDYSNNF GESYSRGTLT PQLRGLLPLG LQTIILDGEM MVWDTNQKRY
360 370 380 390 400
REKGENTDVK NLKPDRSWRP CFVVYDLLYF NGQSLLDLTY IQRSYKLQKL
410 420 430 440 450
IGEQQGVLQL MRGTKIGSIE EFNKLFQQAL DSNAEGIVLK KQSSIYQPGV
460 470 480 490 500
RVGGGWYKDK ADYIKGLITE FDVLIIGGFY NRKRTFIDSF LLGVLQPMAN
510 520 530 540 550
SDSRHEVYSI GCVTNNTRQA VVLNHTLRPH WHDTTKEPPP LWYHYMANEK
560 570 580 590 600
IGSPDLWIDP HNSIILQVKA ADLTPNSAFY TPKALHFPRI ELKRDDKAWN
610 620 630 640 650
ECMTLQEFNQ LCEGSGPIKK LNKRHLCLDD LTTKRKRLRM TPAERRRLGL
660 670 680 690 700
AIYEKRYDVG TSSSCTKLFE GLSFCILSGA PGQSKHKLQE LAAKNGGCIV
710 720 730 740 750
ENPLPNDPKC FCIAGDQTFL VKRLMQQQPC TSDIVRMEWL IRVCQEQELE
760 770 780 790 800
LRPKDLLSAT EPLQDDLAEW FDKLGDSYTK DFASVDELLE LLQDIGKEEL
810 820 830 840 850
AVNHVSQSEI NAFEDKLLGQ ATRNIFRDLH AYFYDPKGDE LSKVLFLQNG
860 870 880 890 900
GTLASESDPQ LNLVFVCLSS DIDDNYFESW LHNHLSSYSG EVLNSAWIHQ
910
SHRERRLLKM SCFSFK
Length:916
Mass (Da):105,009
Last modified:October 14, 2008 - v2
Checksum:iF223C47918AF8DC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH379066 Genomic DNA. Translation: EAL31375.2.
RefSeqiXP_001354322.2. XM_001354286.2.

Genome annotation databases

EnsemblMetazoaiFBtr0287041; FBpp0285479; FBgn0071506.
GeneIDi4814214.
KEGGidpo:Dpse_GA11455.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH379066 Genomic DNA. Translation: EAL31375.2.
RefSeqiXP_001354322.2. XM_001354286.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7237.FBpp0285479.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0287041; FBpp0285479; FBgn0071506.
GeneIDi4814214.
KEGGidpo:Dpse_GA11455.

Organism-specific databases

FlyBaseiFBgn0071506. Dpse\GA11455.

Phylogenomic databases

InParanoidiQ29FM5.
KOiK10777.
OMAiISHFLCA.
OrthoDBiEOG7BKCT2.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution."
    Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L.
    , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A.
    Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25 / Tucson 14011-0121.94Imported.
  2. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25Imported.

Entry informationi

Entry nameiQ29FM5_DROPS
AccessioniPrimary (citable) accession number: Q29FM5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: October 14, 2008
Last modified: January 7, 2015
This is version 58 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.