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Q29FC9 (OTU1_DROPS) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation By similarity.

Catalytic activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Sequence similarities

Contains 1 C2H2-type zinc finger.

Contains 1 OTU domain.

Contains 1 ubiquitin-like domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 358358Ubiquitin thioesterase OTU1
PRO_0000282363

Regions

Domain5 – 8783Ubiquitin-like
Domain161 – 285125OTU
Zinc finger328 – 35225C2H2-type

Sites

Active site1691 By similarity
Active site1721Nucleophile By similarity
Active site3521 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q29FC9 [UniParc].

Last modified April 4, 2006. Version 1.
Checksum: 87FCB64C93082855

FASTA35839,210
        10         20         30         40         50         60 
MTGSFSVKLK SKKGQFIVKD LNQNTTLGEL KTRIAQATAI QELQLHVLVG YPPKPLDLSE 

        70         80         90        100        110        120 
NRENQNLKTV GINSGETLIV EEKAGAAGPT STPLASGSGS STMEDDEALA RRLQAEEDAE 

       130        140        150        160        170        180 
HLRQVSSGGS IETGALNIVQ SLEPVISPEE SGPNGNFNGI LLKKVVPADN SCLFTSIRFV 

       190        200        210        220        230        240 
LNGKVDNEGS EMMRHIIAQE VSADTQQYND AVLGKSNSDY CAWIQKADSW GGAIEVSILS 

       250        260        270        280        290        300 
NYYGIEIDVV DIQNAIINRF GEDKNFGLRV FLLFDGIHYD PLYMETQQNS VPATIFPVEE 

       310        320        330        340        350 
MGVYQQAEQI ANEAKSSRQF TNVDKFTLRC MDCDVMLVGQ GQAQEHAKKT GHENFEEI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH379067 Genomic DNA. Translation: EAL31326.1.
RefSeqXP_001354273.1. XM_001354237.2.

3D structure databases

ProteinModelPortalQ29FC9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7237.FBpp0278050.

Protein family/group databases

MEROPSC85.007.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0279612; FBpp0278050; FBgn0078297.
GeneID4814165.
KEGGdpo:Dpse_GA18292.

Organism-specific databases

FlyBaseFBgn0078297. Dpse\GA18292.

Phylogenomic databases

eggNOGCOG5539.
InParanoidQ29FC9.
KOK13719.
OMAFDGIHYD.
OrthoDBEOG7J1808.

Family and domain databases

InterProIPR003323. OTU.
[Graphical view]
PfamPF02338. OTU. 1 hit.
[Graphical view]
PROSITEPS50802. OTU. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameOTU1_DROPS
AccessionPrimary (citable) accession number: Q29FC9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: April 4, 2006
Last modified: February 19, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase