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Q29EX2 (EIF3E_DROPS) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Eukaryotic translation initiation factor 3 subunit E

Short name=eIF3e
Alternative name(s):
Eukaryotic translation initiation factor 3 subunit 6
Gene names
Name:eIF3-S6
Synonyms:Int6
ORF Names:GA21959
OrganismDrosophila pseudoobscura pseudoobscura (Fruit fly) [Reference proteome]
Taxonomic identifier46245 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity. HAMAP-Rule MF_03004

Subunit structure

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex. The eIF-3 complex interacts with pix By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_03004.

Sequence similarities

Belongs to the eIF-3 subunit E family.

Contains 1 PCI domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Eukaryotic translation initiation factor 3 subunit E HAMAP-Rule MF_03004
PRO_0000365968

Regions

Domain284 – 389106PCI

Sequences

Sequence LengthMass (Da)Tools
Q29EX2 [UniParc].

Last modified April 4, 2006. Version 1.
Checksum: B5F002505FDC1E8B

FASTA43451,037
        10         20         30         40         50         60 
MANFDLTRIN CQYLDRHLTF PLLEFLCGKE IYNQQELLEY ILETVNKTNM IDYTMDTRKR 

        70         80         90        100        110        120 
LNLSQEMPDE LVQRKAEVLA TLKQLQNEVA PIMKATDILK NGESMKDSKT FVNALQKDYN 

       130        140        150        160        170        180 
FKVEHLESAY KLAKYLYECG NYQESTSYLY FCLIVMSPND KNYLNVLWGK LAAEILTLNW 

       190        200        210        220        230        240 
NTALEDLTRL RDYIDSANFS TIQALQQRTW LIHWSVLVFF NHPKGRDLII EMFLYKPLYL 

       250        260        270        280        290        300 
NAIQTMCPHI MRYLATAVVI NRTRRNALKD LIKVIQQESY TYRDPITEFL ECLYVNFDFE 

       310        320        330        340        350        360 
GARLKLHECQ TVILNDFFIV ACLNEFVEDA RLMIFETFCR IHQCITISML ADKLNMKPNE 

       370        380        390        400        410        420 
AECWIVNLIR NARLNAKIDS KLGHVVMGTQ PLSPYQQLVE KIDSLSMRSE HLAGLIERKS 

       430 
KQNNKESIDS WKYY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH379070 Genomic DNA. Translation: EAL29937.1.
RefSeqXP_001352441.1. XM_001352405.2.

3D structure databases

ProteinModelPortalQ29EX2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7237.FBpp0286544.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0288106; FBpp0286544; FBgn0081944.
GeneID4812055.
KEGGdpo:Dpse_GA21959.

Organism-specific databases

FlyBaseFBgn0081944. Dpse\GA21959.

Phylogenomic databases

eggNOGNOG324642.
InParanoidQ29EX2.
KOK03250.
OMADILTGKW.
OrthoDBEOG7QNVKP.
PhylomeDBQ29EX2.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
HAMAPMF_03004. eIF3e.
InterProIPR016650. eIF3e.
IPR019010. eIF3e_N.
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERPTHR10317. PTHR10317. 1 hit.
PfamPF09440. eIF3_N. 1 hit.
PF01399. PCI. 1 hit.
[Graphical view]
PIRSFPIRSF016255. eIF3e_su6. 1 hit.
SMARTSM00088. PINT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEIF3E_DROPS
AccessionPrimary (citable) accession number: Q29EX2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: April 4, 2006
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase