Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Histone-lysine N-methyltransferase

Gene

Dpse\GA21391

Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Ligandi

Metal-binding, S-adenosyl-L-methionineSAAS annotation, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
Name:Dpse\GA21391Imported
ORF Names:Dpse_GA21391Imported, GA21391Imported
OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)Imported
Taxonomic identifieri46245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000001819 Componenti: Partially assembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0081379. Dpse\GA21391.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1419 – 146749AWSInterPro annotationAdd
BLAST
Domaini1470 – 1586117SETInterPro annotationAdd
BLAST
Domaini1594 – 161017Post-SETInterPro annotationAdd
BLAST
Domaini2022 – 2142121BAHInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

InParanoidiQ29DF7.
KOiK06101.
OMAiQCERCEP.
OrthoDBiEOG7ZPNJ4.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR001025. BAH_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
[Graphical view]
PfamiPF01426. BAH. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00249. PHD. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q29DF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSGQNETSA AAKVLETQRT QESGSENEET DSITDQSSQS KSAKSATQFS
60 70 80 90 100
VVQRSDTDGL RMRISAIRPL VPASSKIASV PAPAPAPAPA PGTAPSRKDH
110 120 130 140 150
QSVICKNPLK SRKMSTQDTE SGCSEAKNKA ASKKIKVKRK KITSGSSSTH
160 170 180 190 200
NKTQQHAEHT AKSKKGMLSA FSSDSEDDLP LKVHQQRAPR LLLTAISQAA
210 220 230 240 250
QSASKPLDIG ISSSDNDLPN LVQAAIKRVE SDTEDTTVEG SFRKAAKSKN
260 270 280 290 300
LPQYQSTLLQ DFMEKTQMLG QTGNSKLTEK QLPKAKEETQ LLANVPRKRR
310 320 330 340 350
GRPKKTPVVV PPSRSSGPAI NESADSGVIS TTSTTQSTTP SPKMQTENIV
360 370 380 390 400
PSGTAGAPAA ATSNKPKIDM AYLDKRMYAT ERVLYPSPRN KRRQNNKKPS
410 420 430 440 450
SSTNKEELQL DPLWREIDVN KKFRLRSVSV GAGAASGAGG ASTTICSKIL
460 470 480 490 500
AAKSGYVSDY GSVRHQKSSH NHNSGYKSDA SCKSRYSTKS CMSRRSRAKS
510 520 530 540 550
CGYRSDCKES GKSGMRMRRK RRASMLLKNG AAQEDPTDDL DILLLAGLSL
560 570 580 590 600
GQSSEESNEY ISKPSLQSLP TTSASKKYGE INRYVTTGQY FGRGGGSGSS
610 620 630 640 650
SLPTTNPEIF ISKMMNQRKE TPAPSKSSCK IKSRRSSAAS MCSSYVSGVS
660 670 680 690 700
RVRRRHRRKS FSHSKSLNID SKLLTEIEII TSTFHSRCRI QDDRLTGSSG
710 720 730 740 750
KEKLLAEATK LQATLAAPNT AQQLVLNGGG GGSAASGAAA LPKPLKRAQK
760 770 780 790 800
KRKLSEPLVD FAMLSASANA SVSGTPNGSG SSNGTAKRRH KKSQSNSSSS
810 820 830 840 850
PDDHKLPLKK RHYLLTPGER PLAEAAFANG KLNAEAWAAA AATAKSTAST
860 870 880 890 900
KSQAQFDAKS GKSALTPKKR HLLEQPAAAG VAAAASSASN SPLRIVVDNN
910 920 930 940 950
SISGGKLLDI SPSSLGSLKQ QRRGGVAKQQ KVPHSARDLI QLQSPSGSYP
960 970 980 990 1000
PPGIFEPSVE LEIQIPIGKL NESVITKTEV ESPLLSALDI KEDTKKEIGQ
1010 1020 1030 1040 1050
RVVETLLHKT GGNLLLKRKR KKINRTGFPT VKKKKRKVSV EQQQQPAVVM
1060 1070 1080 1090 1100
VDHPILGMQQ ADEEPLQPIR ETRSSSSAQV QIPANPLLDC ERVPLIGEAR
1110 1120 1130 1140 1150
ETFVARSNQR APRLSVVALE RLQRPQTPAP RGRPRGRRPK DKEALPVVVP
1160 1170 1180 1190 1200
PPPPPPVLDV KPPAKKRGRQ PKPKVEVEHP AAVPQQVKPP QKLNNIKLPA
1210 1220 1230 1240 1250
GVGLKSCQIR LKRRKNLQAT VVDQPQPATV LPVPVEVVSP MEMHATQEEI
1260 1270 1280 1290 1300
DAAAEAKRLE EIPIEHDPLP VSESLHPLPP DNASLSDAGS EDKASTVSTV
1310 1320 1330 1340 1350
SASQRKHSKV KKNYLVAGLF SNYYKQSPMP PPGNKVNKKP GATGQEEQHV
1360 1370 1380 1390 1400
AQGGSLLPPP PYCEKYYRQT EMDFELPYDI WWAYTNDKLP TRHIVPSWNY
1410 1420 1430 1440 1450
RKIRTNVYAE SVRPNLAGFD HPTCNCKNQG EKACLDNCLN RMVYTECSPS
1460 1470 1480 1490 1500
NCPAAEKCRN QKIQRHEVAP GVERFMTLDK GWGVRTKLPI AKGTYILEYV
1510 1520 1530 1540 1550
GEVVTEREFK QRMASIYLND THHYCLHLDG GLVIDGQRMG SDCRFVNHSC
1560 1570 1580 1590 1600
EPNCEMQKWS VNGLSRMVLF AKRPIEQGEE LTYDYNFSLF NPSEGQPCRC
1610 1620 1630 1640 1650
NMPQCRGVIG GKSQRVKPLP AVEAKPVEGC PARNGRQRKH KAKKHAQRMT
1660 1670 1680 1690 1700
GKESPAALAV AKAKMQPLSE KEKKLVKQFN AFLIRNFEKI RKLQAKRAAA
1710 1720 1730 1740 1750
SDSPIHAASN GDGLPGSRPS TPSSNSLLAT QISALCTQRN MKTRGLTQAV
1760 1770 1780 1790 1800
QDPELDKMAK MAVILRDICN AVEALKMSEL LMTVPSNKKK KAMKNSNGKT
1810 1820 1830 1840 1850
HGSGTGSAAR VEFKSIQAHV EQGHYKTPLE YDLQMLQLFA EAKQQHSDDE
1860 1870 1880 1890 1900
GKSKAVQKLL ECYEQQKMAC YTHLLEILGE SESLQSFRPK EEAAPVEEKP
1910 1920 1930 1940 1950
PEIPEVAPLA LATVPLPAVE ASPDEDVIRC ICGLYKDEGL MIQCAKCMVW
1960 1970 1980 1990 2000
QHTECTKADI DADNYQCERC EPREVDREIP LDEYTEEGHR YFLTLMRGNL
2010 2020 2030 2040 2050
QVRQGDAVYV LRDIPIKDAA GNILPSQKHT YETIGAIDYQ ECDIFRVEHL
2060 2070 2080 2090 2100
WKNDDGKRFI FGHHFLRPHE TFHEPSRRFY PNEVVRVSLY EVVPIELVIG
2110 2120 2130 2140 2150
RCWVLDRTTF CKGRPMECPD EDHCFICELR VDKTARFFSK AKANHPACTK
2160 2170 2180 2190 2200
SYAFRKFPEK LKICKSYAPH DVDPSLLKTK KHKTDLEVGG AVPATMHKTS
2210 2220 2230 2240 2250
GRQEQQQQQK AGGRKQRGNS AAAAEATGGA TTVHVVAPVA PNGQVLEKKR
2260 2270 2280 2290 2300
SRLENVLKTV KLKCMDAQTA QEQPIDLSYL WSGRGARQRK TNNQTSSSSN

SVTPSA
Length:2,306
Mass (Da):253,086
Last modified:January 20, 2016 - v3
Checksum:i364701A0670748C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH379070 Genomic DNA. Translation: EAL30457.3.
RefSeqiXP_001352956.3. XM_001352920.3.

Genome annotation databases

EnsemblMetazoaiFBtr0287642; FBpp0286080; FBgn0081379.
GeneIDi4812467.
KEGGidpo:Dpse_GA21391.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH379070 Genomic DNA. Translation: EAL30457.3.
RefSeqiXP_001352956.3. XM_001352920.3.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0287642; FBpp0286080; FBgn0081379.
GeneIDi4812467.
KEGGidpo:Dpse_GA21391.

Organism-specific databases

FlyBaseiFBgn0081379. Dpse\GA21391.

Phylogenomic databases

InParanoidiQ29DF7.
KOiK06101.
OMAiQCERCEP.
OrthoDBiEOG7ZPNJ4.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR001025. BAH_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
[Graphical view]
PfamiPF01426. BAH. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00439. BAH. 1 hit.
SM00249. PHD. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS51038. BAH. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution."
    Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L.
    , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A.
    Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25 / Tucson 14011-0121.94Imported.
  2. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25 / Tucson 14011-0121.94Imported.

Entry informationi

Entry nameiQ29DF7_DROPS
AccessioniPrimary (citable) accession number: Q29DF7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: January 20, 2016
Last modified: March 16, 2016
This is version 73 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.