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Q29CE4

- Q29CE4_DROPS

UniProt

Q29CE4 - Q29CE4_DROPS

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Protein
Submitted name:

GA13730, isoform A

Gene

Dpse\GA13730

Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
GA13730, isoform AImported (EC:1.2.4.2Imported)
Gene namesi
Name:Dpse\GA13730Imported
ORF Names:Dpse_GA13730Imported, GA13730Imported
OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)Imported
Taxonomic identifieri46245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000001819: Chromosome 2

Organism-specific databases

FlyBaseiFBgn0073766. Dpse\GA13730.

Interactioni

Protein-protein interaction databases

STRINGi7237.FBpp0282990.

Family & Domainsi

Phylogenomic databases

InParanoidiQ29CE4.
KOiK15791.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q29CE4-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MLRCFSHAET RFAALLFAQT RPQRFYHSEK GVWGYKPIPK RDYQVAEEVR
60 70 80 90 100
AARNAQANVY RLVEAFRQHG HKLATVNPIS IKAGTEELQE LSPAFYGLQT
110 120 130 140 150
QETVRTAGLL SSPQMAQDVA QLEQLLKDIY CGSAVSAEFS YVENLEEREW
160 170 180 190 200
LARNFESLEQ QHQLPDTERR EIAELLIKSQ AWDNFMALKF PTIKRYGGEG
210 220 230 240 250
AESMLAFFWQ LLRDSVQANI EHVVLAMPHR GRTPLQAALL NMRPAKVFRK
260 270 280 290 300
LSGASEFGED IEAMSDVISH FHVSEQLEVL GRPLNFSMVR NPSHLEAANP
310 320 330 340 350
VAMGKARSKQ QTRGDGAFGP DSQPFGQHVL NVILHGDAAF AGQGINQECL
360 370 380 390 400
NMAYVPHFEV GGSLHLIVNN QVGFTTPGDR GRSTAYTSDL AKSIQAPVFH
410 420 430 440 450
VNGDDPEALA RISKLAFRYQ REFRKDIFID LNCFRRWGHN ELDDPTFTNP
460 470 480 490 500
LVYQIVHQRQ SVPDLYVQRL AKEEVLSESQ AKEMRDNYMK YLGEELALAP
510 520 530 540 550
SYQPPPTYFE KQWAGLQLAP SKELTYWDTG VDYGLLHFIG QQSVSYPADF
560 570 580 590 600
NIHPHLQKTF VNARLKKLEA GSKIDWATAE ALALGSLMYQ GHNIRISGED
610 620 630 640 650
VGRGTFSHRH AMLVDQNTNE MFIPLNSMEG GNGGKLELAH SILSEEAVLG
660 670 680 690 700
FEYGMAIDNP QNLIIWEAQF GDFANGAQII IDAFIVSGET KWMESNALVM
710 720 730 740 750
LLPHGYDGAA SEHSSCRIER FLQLCDSKET SADGDSVNVH IVSPTTPAQY
760 770 780 790 800
YHVLRRQLAR NFRKPLVVVG PKTLLRLPAA TSTHEDFQPG TLFHNVLGDT
810 820 830 840 850
KVQADQVRKV VLCSGKHYYA LAEEREKRQA YDTAILRLES LCPFPLQELQ
860 870 880 890 900
AQLAQYGHVQ SFVWSQEEHR NMGAWTFVRP RFENLIGQQL HYCGRYEAPT
910 920
PATGIGKVHK REVDEIVAAP FEL
Length:923
Mass (Da):104,043
Last modified:October 14, 2008 - v2
Checksum:iD3D70297BDAA834E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000070 Genomic DNA. Translation: EAL26702.2.
RefSeqiXP_001357568.2. XM_001357531.2.

Genome annotation databases

EnsemblMetazoaiFBtr0284552; FBpp0282990; FBgn0073766.
GeneIDi4800345.
KEGGidpo:Dpse_GA13730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000070 Genomic DNA. Translation: EAL26702.2 .
RefSeqi XP_001357568.2. XM_001357531.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7237.FBpp0282990.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0284552 ; FBpp0282990 ; FBgn0073766 .
GeneIDi 4800345.
KEGGi dpo:Dpse_GA13730.

Organism-specific databases

FlyBasei FBgn0073766. Dpse\GA13730.

Phylogenomic databases

InParanoidi Q29CE4.
KOi K15791.

Family and domain databases

Gene3Di 3.40.50.970. 2 hits.
InterProi IPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view ]
PANTHERi PTHR23152. PTHR23152. 1 hit.
Pfami PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view ]
PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTi SM00861. Transket_pyr. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 2 hits.
TIGRFAMsi TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution."
    Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L.
    , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A.
    Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25 / Tucson 14011-0121.94Imported.
  2. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25Imported.

Entry informationi

Entry nameiQ29CE4_DROPS
AccessioniPrimary (citable) accession number: Q29CE4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: October 14, 2008
Last modified: October 1, 2014
This is version 50 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3