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Protein

Cardio acceleratory peptide 2b

Gene

capa

Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

CAP-1 and CAP-2, but not CAP-3 are ligands for the Capa receptor. CAP-1 and CAP-2 are probably components of the signal transduction pathway that leads to Malpighian tubule fluid secretion via the second messenger nitric oxide (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNeuropeptide

Names & Taxonomyi

Protein namesi
Recommended name:
Cardio acceleratory peptide 2b
Alternative name(s):
Capability protein
Myotropin-CAP2b-like protein
Cleaved into the following 3 chains:
Alternative name(s):
Pyrokinin-1
Gene namesi
Name:capaBy similarity
ORF Names:GA13779
OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)
Taxonomic identifieri46245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000001819 Componentsi: Chromosome 2, Partially assembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0073815 Dpse\GA13779

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
PropeptideiPRO_000033924427 – 33By similarity7
PeptideiPRO_000033924536 – 47CAP-1By similarityAdd BLAST12
PropeptideiPRO_000033924650 – 85By similarityAdd BLAST36
PeptideiPRO_000033924788 – 96CAP-2By similarity9
PropeptideiPRO_000033924899 – 117By similarityAdd BLAST19
PeptideiPRO_0000339249120 – 134CAP-3By similarityAdd BLAST15
PropeptideiPRO_0000339250138 – 155By similarityAdd BLAST18

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei47Valine amideBy similarity1
Modified residuei96Valine amideBy similarity1
Modified residuei134Leucine amideBy similarity1

Keywords - PTMi

Amidation, Cleavage on pair of basic residues

Proteomic databases

PRIDEiQ29CA0

Expressioni

Gene expression databases

BgeeiFBgn0073815

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the pyrokinin family.Sequence analysis

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiQ29CA0
OMAiYNEADFQ

Family and domain databases

PROSITEiView protein in PROSITE
PS00539 PYROKININ, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q29CA0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAIFSLYNI VSAILLLVLL AEFSTAELNH DKNRRGANMG LYAFPRVGRS
60 70 80 90 100
DPSLANSLRD ASDAAVFDGL YGDASQEDYN EADYQKRAGL VAFPRVGRSD
110 120 130 140 150
AELRKFAHLL ALQQVLDKRT GPSASSGLWF GPRLGKRSVD AKAFSDASKG

QQEFN
Length:155
Mass (Da):16,958
Last modified:June 10, 2008 - v2
Checksum:i4572C392A8F91481
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000070 Genomic DNA Translation: EAL26746.2
RefSeqiXP_001357612.2, XM_001357575.3

Genome annotation databases

EnsemblMetazoaiFBtr0284510; FBpp0282948; FBgn0073815
GeneIDi4800261
KEGGidpo:Dpse_GA13779

Similar proteinsi

Entry informationi

Entry nameiCP2B_DROPS
AccessioniPrimary (citable) accession number: Q29CA0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 10, 2008
Last modified: May 23, 2018
This is version 43 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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