Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q29AU6 (RUMI_DROPS) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length409 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has O-glucosyltransferase activity: catalyzes the reaction that attaches glucose through an O-glycosidic linkage to a conserved serine residue in epidermal growth factor-like repeats. Regulates Notch signaling by glucosylating Notch in the ER, glucosylation is required for the correct folding and cleavage of Notch By similarity. UniProtKB Q8T045

Pathway

Protein modification; protein glycosylation.

Subcellular location

Endoplasmic reticulum lumen By similarity UniProtKB Q8T045.

Sequence similarities

Belongs to the glycosyltransferase 90 family.

Sequence caution

The sequence EAL27253.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 409389O-glucosyltransferase rumi
PRO_0000342688

Regions

Motif406 – 4094Prevents secretion from ER

Sequences

Sequence LengthMass (Da)Tools
Q29AU6 [UniParc].

Last modified April 4, 2006. Version 1.
Checksum: EC695CBD0699DCE3

FASTA40947,314
        10         20         30         40         50         60 
MLINVVLIIL LVGLNGKASG QNQGLCSPDE NASCADSSDT QDEFSFNILR KIKKALASYQ 

        70         80         90        100        110        120 
PCSSDANDAN CSCHAAVIKS DLAPYKATGV SRQMIESSAR YGTRYKIYEK RLYREENCMF 

       130        140        150        160        170        180 
PARCQGIEHF LLPLVATLPD MDLVINTRDY PQINMAWGNG AQGPILSFSK TKDHRDIMYP 

       190        200        210        220        230        240 
AWTFWAGGPA TKLHPRGIGR WDLMREKLEK RAAAIPWSQK RELGFFRGSR TSDERDSLIL 

       250        260        270        280        290        300 
LSRRNPELVE AQYTKNQGWK SPKDTLDAPP AGEVSFEDHC KYKYLFNFRG VAASFRLKHL 

       310        320        330        340        350        360 
FLCQSLVFHV GDEWQEFFYD QLKPWVHYVP LKNYPSQQEY EELLTFFRKN DALAQEIAQR 

       370        380        390        400 
GRDFIWQHLR MKDIKCYWRR LLKSYVKLLT YEVQPEDQLI HIQPAKDEL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CM000070 Genomic DNA. Translation: EAL27253.1. Sequence problems.
RefSeqXP_001358116.1. XM_001358079.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7237.FBpp0283469.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0285031; FBpp0283469; FBgn0076066.
GeneID4800928.
KEGGdpo:Dpse_GA16050.

Organism-specific databases

FlyBaseFBgn0076066. Dpse\GA16050.

Phylogenomic databases

eggNOGNOG248922.
InParanoidQ29AU6.
KOK13667.
OMACANDETL.
OrthoDBEOG7R831J.

Enzyme and pathway databases

UniPathwayUPA00378.

Family and domain databases

InterProIPR006598. LipoPS_modifying.
[Graphical view]
PfamPF05686. Glyco_transf_90. 1 hit.
[Graphical view]
SMARTSM00672. CAP10. 1 hit.
[Graphical view]
PROSITEPS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRUMI_DROPS
AccessionPrimary (citable) accession number: Q29AU6
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: April 4, 2006
Last modified: March 19, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase