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Q29AP0

- PTC71_DROPS

UniProt

Q29AP0 - PTC71_DROPS

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Protein

Protein phosphatase PTC7 homolog fig

Gene

fig

Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Magnesium or manganese.By similarityCurated

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi90 – 901Manganese 1By similarity
Metal bindingi90 – 901Manganese 2By similarity
Metal bindingi91 – 911Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi236 – 2361Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: UniProtKB

GO - Biological processi

  1. dephosphorylation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase PTC7 homolog fig
Alternative name(s):
Fos intronic gene protein (EC:3.1.3.16)
Gene namesi
Name:figBy similarity
ORF Names:GA20482
OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)
Taxonomic identifieri46245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000001819: Chromosome 2, UP000001819: Partially assembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0080477. Dpse\GA20482.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 340340Protein phosphatase PTC7 homolog figPRO_0000377401Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7237.FBpp0283509.

Structurei

3D structure databases

ProteinModelPortaliQ29AP0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini56 – 312257PP2C-likeSequence AnalysisAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Sequence Analysis
Contains 1 PP2C-like domain.Sequence Analysis

Phylogenomic databases

eggNOGiCOG0631.
InParanoidiQ29AP0.
KOiK17508.
OrthoDBiEOG7DRJ3F.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
[Graphical view]
PfamiPF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.

Sequencei

Sequence statusi: Complete.

Q29AP0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAFMRSKPSL GSLARVAFRW CGPGVGLVNY SQEPYLVKAV QGKSKPRSPT
60 70 80 90 100
LQSAMQPRAQ AETIQAPKCF GEDSFFFSST PKADVMGVAD GVGGWRDRGI
110 120 130 140 150
DAGRFSRDLM QRCFVHAQKP TFDGRNPRQL LSECYGEMKR KWKPILGSST
160 170 180 190 200
ACVVAFNRSE SALYTANLGD SGYVVIRNGS VLDRSEEQTH FFNMPFQLTV
210 220 230 240 250
PPPDSNREMW FCDDPSEAVA TRLLLQPDDL VLVATDGLFD NMPEQMLLEM
260 270 280 290 300
LSKVQGVHEQ KAIQEAVNRV VERAGALSIN PIYKSPFCLR ALENNVAYGG
310 320 330 340
GGKPDDITVV LASVAMRQCN TVGDSNESKG SDLRPRLSFP
Length:340
Mass (Da):37,443
Last modified:October 14, 2008 - v2
Checksum:i280EE1765CA1AABA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000070 Genomic DNA. Translation: EAL27309.2.
RefSeqiXP_001358172.2. XM_001358135.2.

Genome annotation databases

EnsemblMetazoaiFBtr0285071; FBpp0283509; FBgn0080477.
GeneIDi4800997.
KEGGidpo:Dpse_GA20482.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000070 Genomic DNA. Translation: EAL27309.2 .
RefSeqi XP_001358172.2. XM_001358135.2.

3D structure databases

ProteinModelPortali Q29AP0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7237.FBpp0283509.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0285071 ; FBpp0283509 ; FBgn0080477 .
GeneIDi 4800997.
KEGGi dpo:Dpse_GA20482.

Organism-specific databases

FlyBasei FBgn0080477. Dpse\GA20482.

Phylogenomic databases

eggNOGi COG0631.
InParanoidi Q29AP0.
KOi K17508.
OrthoDBi EOG7DRJ3F.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
[Graphical view ]
Pfami PF07228. SpoIIE. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution."
    Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L.
    , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A.
    Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25 / Tucson 14011-0121.94.

Entry informationi

Entry nameiPTC71_DROPS
AccessioniPrimary (citable) accession number: Q29AP0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: October 14, 2008
Last modified: October 1, 2014
This is version 48 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3