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Unreviewed, UniProtKB/TrEMBL Q29971 (Q29971_HUMAN)

Last modified February 9, 2010. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Cell surface glycoprotein EMBL AAA63218.1
Gene names
Name: HLA-Dw12 EMBL AAA63218.1
OrganismHomo sapiens (Human) EMBL AAA63218.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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Sequences

Sequence LengthMass (Da)Tools
Q29971-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: C19F83ECDB66450D

FASTA26629,955
        10         20         30         40         50         60 
MVCLNVPGGS YMAKLTVTLM VLSSPLALAG DTRPRFLQQD KYECHFFNGT ERVRFLHRGI 

        70         80         90        100        110        120 
YNQEENVRFD SDVGEYRAVT ELGRPDAEYW NSQKDFLEDR RAAVDTYCRH NYGVGESFTV 

       130        140        150        160        170        180 
QRRVEPKVTV YPARTQTLQH HNLLVCSVNG FYPGSIEVRW FRNSQEEKAG VVSTGLIQNG 

       190        200        210        220        230        240 
DWTFQTLVML ETVPRSGEVY TCQVEHPSVT SPLTVEWRAQ SESAQSKMLS GVGGFVLGLL 

       250        260 
FLGAGLFIYF KNQKGHSGLH PTGLVS

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References

[1]"Structural analysis of human major histocompatibility complex class II genes"
Yasunami M.
Fukuoka Igaku Zasshi 79:153-167(1988) [PubMed: 3371836] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"cDNA cloning and sequencing reveals that the electrophoretically constant DR beta 2 molecules, as well as the variable DR beta 1 molecules, from HLA-DR2 subtypes have different amino acid sequences including a hypervariable region for a functionally important epitope."
Wu S.K., Yabe T., Madden M., Saunders T.L., Bach F.H.
J. Immunol. 138:2953-2959(1987) [PubMed: 3571980] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Polymorphism of human Ia antigens generated by reciprocal intergenic exchange between two DR beta loci."
Wu S., Saunders T.L., Bach F.H.
Nature 324:676-679(1986) [PubMed: 3099214] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M57648 mRNA. Translation: AAA63218.1.
IPIIPI00107714.
PIRC32526.
D25239.
I67726.
PT0170.
PT0171.
UniGeneHs.534322

3D structure databases

HSSPHSSP built from PDB template 1FV1 based on UniProtKB Q30154.
SMRQ29971. Positions 30-219.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ29971.

Proteomic databases

PRIDEQ29971.

Genome annotation databases

EnsemblENST00000374975; ENSP00000364114; ENSG00000198502; Homo sapiens. [Genome view]

Organism-specific databases

HGNCHGNC:4953. HLA-DRB5.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ29971.

Family and domain databases

InterProIPR007110. Ig-like.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR000353. MHC_II_b_N.
[Graphical view]
Gene3DG3DSA:2.60.40.10. Ig-like_fold. 1 hit.
PfamPF07654. C1-set. 1 hit.
PF00969. MHC_II_beta. 1 hit.
[Graphical view]
ProDomPD000328. MHC_II_b_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00407. IGc1. 1 hit.
[Graphical view]
PROSITEPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameQ29971_HUMAN
AccessionPrimary (citable) accession number: Q29971
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: February 9, 2010
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information