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Q29818

- Q29818_HUMAN

UniProt

Q29818 - Q29818_HUMAN

Protein
Submitted name:

MHC class II HLA-DR-beta-7

Gene

HLA-DRB7

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
  1. Functioni

    GO - Biological processi

    1. antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
    2. immune response Source: InterPro

    Keywords - Biological processi

    Immunity

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MHC class II HLA-DR-beta-7Imported
    Gene namesi
    Name:HLA-DRB7Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. MHC class II protein complex Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane, MHC IIUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliQ29818.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    TransmembraneUniRule annotation

    Family and domain databases

    Gene3Di3.10.320.10. 1 hit.
    InterProiIPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR000353. MHC_II_b_N.
    [Graphical view]
    PfamiPF00969. MHC_II_beta. 1 hit.
    [Graphical view]
    ProDomiPD000328. MHC_II_b_N. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SMARTiSM00921. MHC_II_beta. 1 hit.
    [Graphical view]
    SUPFAMiSSF54452. SSF54452. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q29818-1 [UniParc]FASTAAdd to Basket

    « Hide

    LKQDKFECHF FNGTERVRYL HRGIYNQEEN VRFDSDVGEY RAVTELGRPV   50
    AESWNSQKDF LERRRAEVDT VCRHNYGVGE SF 82
    Length:82
    Mass (Da):9,789
    Last modified:November 1, 1996 - v1
    Checksum:i74855FD31DDE6D5B
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei82 – 821Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M96130 Unassigned DNA. Translation: AAA03144.1.
    PIRiPT0162.
    UniGeneiHs.534322.
    Hs.696211.
    Hs.716081.
    Hs.723344.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M96130 Unassigned DNA. Translation: AAA03144.1 .
    PIRi PT0162.
    UniGenei Hs.534322.
    Hs.696211.
    Hs.716081.
    Hs.723344.

    3D structure databases

    ProteinModelPortali Q29818.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.10.320.10. 1 hit.
    InterProi IPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR000353. MHC_II_b_N.
    [Graphical view ]
    Pfami PF00969. MHC_II_beta. 1 hit.
    [Graphical view ]
    ProDomi PD000328. MHC_II_b_N. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SMARTi SM00921. MHC_II_beta. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54452. SSF54452. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Shared class II MHC polymorphisms between humans and chimpanzees."
      Fan W.M., Kasahara M., Gutknecht J., Klein D., Mayer W.E., Jonker M., Klein J.
      Hum. Immunol. 26:107-121(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Mhc-DRB diversity of the chimpanzee (Pan troglodytes)."
      Kenter M., Otting N., Anholts J., Jonker M., Schipper R., Bontrop R.E.
      Immunogenetics 37:1-11(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ29818_HUMAN
    AccessioniPrimary (citable) accession number: Q29818
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.